Разработка методики изучения антимикробной активности прототипов твердых лекарственных форм с функцией контролируемого высвобождения антибиотиков
| Parent link: | Перспективы развития фундаментальных наук=Prospects of Fundamental Sciences Development: сборник научных трудов XVIII Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 27-30 апреля 2021 г./ Национальный исследовательский Томский политехнический университет (ТПУ) ; под ред. И. А. Курзиной, Г. А. Вороновой.— , 2021 Т. 4 : Биология и фундаментальная медицина.— 2021.— [С. 10-12] |
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| Summary: | Заглавие с экрана Currently, there are many methods for testing the antibacterial activity of solid dosage forms intended for targeted delivery and controlled release of drugs. The standard diffusion method has a number of limitations, the main one of which is the impossibility of assessing the antibacterial activity of samples in vitro under conditions of skin damage. Infiltration method has been developed, which allows a deeper assessment of the antibacterial activity of solid dosage forms. As a result of a study on a polymer scaffold model, it was found that targeted delivery of chloramphenicol can potentially increase the growth inhibition of both S. aureus and E. coli, which will further reduce the systemic dose of drugs prescribed to patients. |
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2021
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| Online Access: | http://earchive.tpu.ru/handle/11683/68334 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=633376 |