Результати пошуку - "erythropoietin"

Tissue-Protective Cytokines Methods and Protocols /

Зміст: “...Erythropoietin and Engineered Innate Repair Activators -- Epo and Non-hematopoietic Cells: What Do We Know? ...”
Отримати повний текст

Antiepileptic Drug Discovery Novel Approaches /

Зміст: “...-- Glutamate Receptors as Targets for Novel Antiepileptic Drug Therapy -- Neurosteroid Regulation of Seizures: Role of GABAA Receptor Plasticity -- Erythropoietin as Potential Neuroprotective and Antiepileptogenic Agent in Epilepsy and Refractory Epilepsy -- Caloric Restriction and Dietary Treatments of Epilepsy: Mechanistic Insights for Drug Discovery -- Gene Therapy in Epilepsy -- Human Brain Tissue as a Model for the Study of Epilepsy -- The Blood-Brain Barrier and the Design of New Antiepileptic Drugs -- Virtual Screening Applications in the Search of Novel Antiepileptic Drug Candidates -- Discovering New Antiepileptic Drugs Addressing the Transporter Hypothesis of Refractory Epilepsy: Ligand-Based Approximations -- Discovering New Antiepileptic Drugs Addressing the Transporter Hypothesis of Refractory Epilepsy: Structure-Based Approximations -- Nanoformulations of Antiepileptic Drugs: In Vitro and In Vivo Studies -- Side Effects of Antiepileptic Drugs -- Network Pharmacology and Epilepsy -- The Importance of Drug Repurposing in the Field of Antiepileptic Drug Development....”
Отримати повний текст

Fragment-Based Methods in Drug Discovery

Зміст: “...Solvation Methods for Protein-Ligand Docking -- Binding Site Druggability Assessment in Fragment-Based Drug Design -- Generating "Fragment-Based Virtual Library" Using Pocket Similarity Search of Ligand-Receptor Complexes -- Virtual Fragment Preparation for Computational Fragment-Based Drug Design -- Fragment Library Design: Using Cheminformatics and Expert Chemists to Fill Gaps in Existing Fragment Libraries -- Protocol for Fragment Hopping -- Site Identification by Ligand Competitive Saturation (SILCS) Simulations for Fragment-Based Drug Design -- A Computational Fragment-Based De Novo Design Protocol Guided by Ligand Efficiency Indices (LEI) -- Scoring Functions for Fragment-Based Drug Discovery -- Computational Methods for Fragment-Based Ligand Design: Growing and Linking -- Design Strategies for Computational Fragment-Based Drug Design -- Protein Binding Site Analysis for Drug Discovery Using a Computational Fragment-Based Method -- Fragment-Based Design of Kinase Inhibitors: A Practical Guide -- Designing a Small Molecule Erythropoietin Mimetic -- Designing an Orally Available Non-Toxic p38 Inhibitor with a Fragment-Based Strategy....”
Отримати повний текст

Development of Optimized Strategies for Growth Factor Incorporation onto Electrospun Fibrous Scaffolds To Promote Prolonged Release

Отримати повний текст

Synthetic mRNA Production, Introduction Into Cells, and Physiological Consequences /

Зміст: “...Synthetic mRNA: Production, Introduction into Cells, and Physiological Consequences -- Synthetic Capped mRNAs for Cap-Specific Photo-Crosslinking Experiments -- Enzymatic Modification of 5’-Capped RNA and Subsequent Labeling by Click Chemistry -- Preparation of Functional, Fluorescently Labeled mRNA Capped with Anthraniloyl-m7GpppG -- Intronless b-Globin Reporter: A Tool for Studying Nuclear RNA Stability Elements -- Synthetic mRNA with Superior Properties that Mimics the Intracellular Fates of Natural Histone mRNA -- Engineering WT1-Encoding mRNA to Increase Translational Efficiency in Dendritic Cells -- Electroporation of Alphavirus RNA Translational Reporters into Fibroblastic and Myeloid Cells as a Tool to Study the Innate Immune System -- GMP-Grade mRNA Electroporation of Dendritic Cells for Clinical Use -- Large Scale mRNA Transfection of Dendritic Cells by Electroporation in Continuous Flow Systems -- FLT3 Ligand as a Molecular Adjuvant for Naked RNA Vaccines -- Transfecting Human Monocytes with RNA -- In Vitro Synthesis, Delivery and Bioavailability of Exogenous mRNA in Gene Transfer Mediated byPiggyBac Transposition -- Transfection of Human Keratinocytes with Nucleoside-Modified mRNA Encoding CPD-Photolyase to Repair DNA Damage -- Delivery of Synthetic mRNA Encoding FOXP3 Antigen into Dendritic Cells for Inflammatory Breast Cancer Immunotherapy -- Immune Monitoring using mRNA-Transfected Dendritic Cells -- Transfection of Tumor-Infiltrating T Cells with mRNA Encoding CXCR2 -- mRNA Electroporation of Dendritic Cells with WT1, Survivin and TriMix (A Mixture of caTLR4, CD40L, and CD70) -- Redirecting T Cell Specificity Using T Cell Receptor Messenger RNA Electroporation -- Measuring Hematocrit in Mice Injected with In Vitro-Transcribed Erythropoietin mRNA -- Genetic Modification of Human Pancreatic Progenitor Cells through Modified mRNA....”
Отримати повний текст