Antibody Engineering Volume 2

Podrobná bibliografie
Korporativní autor: SpringerLink (Online service)
Další autoři: Kontermann, Roland E. (Editor), Dübel, Stefan (Editor)
Shrnutí:XII, 589 p.
text
Jazyk:angličtina
Vydáno: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2010.
Vydání:2nd ed. 2010.
Edice:Springer Protocols Handbooks,
Témata:
On-line přístup:https://doi.org/10.1007/978-3-642-01147-4
Médium: Elektronický zdroj Kniha
Obsah:
  • Bioinformatics of Antigen-binding Sites
  • Analysis of Single Chain Antibody Sequences Using the VBASE2 Fab Analysis Tool
  • Standardized Sequence and Structure Analysis of Antibody Using IMGT®
  • Protein Sequence and Structure Analysis of Antibody Variable Domains
  • Generation of Antibody Fragments and Their Derivatives
  • scFv by Two-Step Cloning
  • Bivalent Diabodies
  • Generation of Single-Chain Fv Fragments and Multivalent Derivatives scFv-Fc and scFv-CH3 (Minibodies)
  • Miniantibodies
  • Generation of Stably Transfected Eukaryotic Cell Lines Producing ImmunoRNAse Fusion Proteins
  • Antibody–Cytokine Fusion Proteins with Members of the TNF-Family
  • Recombinant Immunotoxins for Treating Cancer
  • T Bodies
  • Expressing Intrabodies in Mammalian Cells
  • Phenotypic Knockdown with Intrabodies
  • Disulfide-Stabilized Fv Fragments
  • PEGylation of Antibody Fragments to Improve Pharmacodynamics and Pharmacokinetics
  • Fusion Proteins with Improved PK
  • In Vivo Biotinylated scFv Fragments
  • Bispecific Diabodies and Single-Chain Diabodies
  • Generation and Characterization of a Dual Variable Domain Immunoglobulin (DVD-Ig™) Molecule
  • Isolation of Antigen-Specific Nanobodies
  • CDR-FR Peptides
  • Production of Antibody Fragments
  • Purification and Characterization of His-Tagged Antibody Fragments
  • Production of Antibody Fragments in the Gram-Positive Bacterium Bacillus megaterium
  • Analysis and Purification of Antibody Fragments Using Protein A, Protein G, and Protein L
  • Purification and Analysis of Strep-tagged Antibody-Fragments
  • Production of Antibodies and Antibody Fragments in Escherichia coli
  • Improving Expression of scFv Fragments by Co-expression of Periplasmic Chaperones
  • Bioreactor Production of scFv Fragments in Pichia pastoris
  • Expression of Antibody Fragments in Transgenic Plants
  • Transient Production of scFv-Fc Fusion Proteins in Mammalian Cells
  • Recombinant Antibody Molecules in Nanobiotechnology and Proteomics
  • Immunoliposomes
  • Targeted Polymeric Nanoparticles.-Antibody Microarrays for Expression Analysis
  • Evaluation of Recombinant Antibodies on Protein Microarrays Applying the Multiple Spotting Technique
  • Preclinical and Clinical Development
  • Xenograft Mouse Models for Tumour Targeting
  • Xenograft Mouse Models for Tumour Targeting
  • Imaging Tumor Xenografts Using Radiolabeled Antibodies
  • Human Anti-antibody Response
  • IP Issues in the Therapeutic Antibody Industry.