The Myc Gene Methods and Protocols /

מידע ביבליוגרפי
מחבר תאגידי: SpringerLink (Online service)
מחברים אחרים: Soucek, Laura (Editor), Sodir, Nicole M. (Editor)
סיכום:XI, 282 p. 44 illus., 29 illus. in color.
text
שפה:אנגלית
יצא לאור: Totowa, NJ : Humana Press : Imprint: Humana, 2013.
מהדורה:1st ed. 2013.
סדרה:Methods in Molecular Biology, 1012
נושאים:
גישה מקוונת:https://doi.org/10.1007/978-1-62703-429-6
פורמט: אלקטרוני ספר
תוכן הענינים:
  • The Myc world within Reach
  • Methods for the Expression, Purification, Preparation and Biophysical Characterization of Constructs of the c-Myc and Max b-HLH-LZs
  • Analyzing Myc in Cell Transformation and Evolution
  • Identifying Myc Interactors
  • Detection of c-Myc Protein-Protein Interactions And Phosphorylation Status by Immunoprecipitation
  • An Efficient Way of Studying Protein–Protein Interactions Involving HIF-α, c-Myc, and Sp1
  • Methods for Determining Myc-induced Apoptosis
  • Methods to Study Myc-regulated Cellular Senescence
  • Chromatin Immunoprecipitation Assays for Myc and N-Myc
  • Methods to Quantify microRNAs in the Myc Gene Network for Posttranscriptional Gene Repression
  • Genome-wide Analysis of c-MYC-regulated mRNAs and miRNAs, and c-MYC DNA-binding by Next Generation Sequencing
  • A High Throughput siRNA Screening Platform to Identify MYC Synthetic Lethal Genes as Candidate Therapeutic Targets
  • Investigating Myc-dependent Translational Regulation in Normal and Cancer Cells
  • Studying Myc’s Role in Metabolism Regulation
  • Generation of a Tetracycline Regulated Mouse Model of MYC-induced T-cell Acute Lymphoblastic Leukemia
  • Methods to Assess Myc Function in Intestinal Homeostasis, Regeneration and Tumourigenesis
  • Detection of c-myc Amplification in Formalin-fixed Paraffin-Embedded Tumor Tissue by Chromogenic in situ Hybridization (CIHS)
  • Cell-Based Methods for the Identification of MYC-Inhibitory Small Molecules.