Kinase Inhibitors Methods and Protocols /

書目詳細資料
企業作者: SpringerLink (Online service)
其他作者: Kuster, Bernhard (Editor)
總結:XI, 256 p. 47 illus., 11 illus. in color.
text
語言:英语
出版: Totowa, NJ : Humana Press : Imprint: Humana, 2012.
版:1st ed. 2012.
叢編:Methods in Molecular Biology, 795
主題:
在線閱讀:https://doi.org/10.1007/978-1-61779-337-0
格式: 電子 圖書
書本目錄:
  • Targeting Cancer with Small Molecular Weight Kinase Inhibitors
  • Small Molecule Protein and Lipid Kinase Inhibitors in Inflammation and Specific Models for their Evaluation
  • Measuring the Activity of Leucine Rich Repeat Kinase 2 (LRRK2) – A Kinase Involved in Parkinson’s Disease
  • Measuring PI3K Lipid Kinase Activity
  • A Fluorescence Polarization Assay for the Discovery of Inhibitors of the Polo-box Domain of Polo-like Kinase 1
  • Assessment of Hepatotoxicity Potential of Drug Candidate Molecules Including Kinase Inhibitors by Hepatocyte Imaging Assay Technology and Bile Flux Imaging Assay Technology
  • Kinase Inhibitor Selectivity Profiling using Differential Scanning Fluorimetry
  • Chemoproteomic Characterization of Protein Kinase Inhibitors using Immobilized ATP
  • Proteome-wide identification of staurosporine-binding kinases using Capture Compound Mass Spectrometry
  • Affinity Purification of Proteins Binding to Kinase Inhibitors Immobilised on Self Assembling Monolayers
  • Kinase Inhibitor Profiling using Chemoproteomics
  • Covalent Crosslinking of Kinases with Their Corresponding Peptide Substrates
  • Receptor Tyrosine Kinase Inhibitor Profiling using Bead-based Multiplex Sandwich Immunoassays
  • Monitoring PhosphoproteomicResponse To Targeted Kinase Inhibitors Using Reverse-Phase Protein Microarrays
  • Measuring Phosphorylation Specific Changes in Response to Kinase Inhibitors in Mammalian Cells Using Quantitative Proteomics
  • Investigation of Acquired Resistance to EGFR-Targeted Therapies in Lung Cancer Using cDNA Microarrays.