Drug Design and Discovery Methods and Protocols /

التفاصيل البيبلوغرافية
مؤلف مشترك: SpringerLink (Online service)
مؤلفون آخرون: Satyanarayanajois, Seetharama D. (المحرر)
الملخص:XI, 284 p.
text
اللغة:الإنجليزية
منشور في: Totowa, NJ : Humana Press : Imprint: Humana, 2011.
الطبعة:1st ed. 2011.
سلاسل:Methods in Molecular Biology, 716
الموضوعات:
الوصول للمادة أونلاين:https://doi.org/10.1007/978-1-61779-012-6
التنسيق: الكتروني كتاب الكتروني
جدول المحتويات:
  • Virtual Screening for Lead Discovery
  • Computer-Aided Drug Discovery and Development
  • Using Active Site Mapping and Receptor-Based Pharmacophore Tools: Prelude to Docking and De Novo/Fragment-Based Ligand Design
  • Methods for Evaluation of Structural and Biological Properties of Anti-Invasive Natural Products
  • Solid-Phase Peptide Synthesis Using Microwave Irradiation
  • Fluorescent and Lanthanide Labeling for Ligand Screens, Assays, and Imaging
  • DNA-Directed Assembly Microarray for Protein and Small Molecule Inhibitor Screening
  • Selection of Peptide Ligands for Human Placental Transcytosis Systems Using In vitro Phage Display
  • Optimization of the Tetrazolium Dye (MTT) Colorimetric Assay for Cellular Growth and Viability
  • Imaging NF- κB Signaling in Mice for Screening Anti-Cancer Drugs
  • Evaluation of Anticancer Agents Using Flow Cytometry Analysis of Cancer Stem Cells
  • Chemical Screening with Zebrafish Embryos.- iTRAQTM Labeling Coupled with LC-MALDI Mass Spectrometry for Monitoring Temporal Response of Colorectal Cancer Cells to Butyrate Treatment
  • Heterotypic Cell Adhesion Assay for the Study of Cell Adhesion Inhibition
  • Evaluation of Antibacterial Activity of Proteins and Peptides Using a Specific Animal Model for Wound Healing
  • In vitro Immunogenicity Risk Assessment of Therapeutic Proteins in Preclinical Setting.