Therapeutic Antibodies Methods and Protocols /
| Autor Corporativo: | |
|---|---|
| Outros Autores: | |
| Resumo: | XVIII, 585 p. text  | 
| Idioma: | inglês | 
| Publicado em: | 
        Totowa, NJ :
          Humana Press : Imprint: Humana,
    
        2009.
     | 
| Edição: | 1st ed. 2009. | 
| coleção: | Methods in Molecular Biology,
              525             | 
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1007/978-1-59745-554-1 | 
| Formato: | Recurso Eletrônico Livro | 
                Sumário: 
            
                  - Recombinant Antigens
 - Therapeutic Antibodies: Current State and Future Trends – Is a Paradigm Change Coming Soon?
 - Preparation of Recombinant Viral Glycoproteins for Novel and Therapeutic Antibody Discovery
 - Antibody Libraries
 - Design of a Human Synthetic Combinatorial Library of Single-Chain Antibodies
 - Construction of a Human Antibody Domain (VH) Library
 - Generation and Selection of Rabbit Antibody Libraries by Phage Display
 - Construction of a Large Naïve Human Phage-Displayed Fab Library Through One-Step Cloning
 - Antibody Discovery
 - Identification of Target and Function Specific Antibodies for Effective Drug Delivery
 - Screening of Specific Internalization Fab Fragment from Human Naive Phage Library by Combinational Bio-Panning
 - Competitive Antigen Panning for Selection of HIV-1 Neutralizing Human Monoclonal Antibodies Specific for gp41
 - Selection of Non-aggregating VH Binders from Synthetic VH Phage-Display Libraries
 - Isolation of Full-Length IgG Antibodies from Combinatorial Libraries Expressed in Escherichia coli
 - Multiplexed Flow Cytometry: High-Throughput Screening of Single-Chain Antibodies
 - Human Antibody Repertoires
 - Rapid Screening Platform for Stabilization of scFvs in Escherichia coli
 - Antibody Engineering
 - In Vitro Antibody Affinity Maturation Targeting Germline Hotspots
 - Affinity Maturation by Phage Display
 - Production of Chimeric Heavy-Chain Antibodies
 - Mammalian Cell Display for Antibody Engineering
 - Improving Antibody Binding Affinity and Specificity for Therapeutic Development
 - Construction and Production of an IgG-Like Tetravalent Bispecific Antibody for Enhanced Therapeutic Efficacy
 - Deimmunization of Monoclonal Antibodies
 - Anti-CD22 Onconase: Preparation and Characterization
 - Antibody–Cytotoxic Agent Conjugates:Preparation and Characterization
 - Antibody Preclinical Development
 - High-Level Production of a Humanized ImmunoRNase Fusion Protein from Stably Transfected Myeloma Cells
 - Antibody Fragment Expression and Purification
 - Scaling-Up and Production of Therapeutic Antibodies for Preclinical Studies
 - Antibody Production by the Gram-Positive Bacterium Bacillus megaterium
 - Neutralization of HIV by Antibodies
 - Dynamics of Antibody Domains Studied by Solution NMR
 - In Vivo Method for Establishing Synergy Between Antibodies to Epidermal Growth Factor Receptor and Vascular Endothelial Growth Factor Receptor-2
 - Passive Immunization with Human Neutralizing Monoclonal Antibodies Against HIV-1 in Macaque Models: Experimental Approaches
 - Antibody Sequence Analysis
 - Organizing, Exploring, and Analyzing Antibody Sequence Data: The Case for Relational-Database Managers.