Biomarker Methods in Drug Discovery and Development

Dades bibliogràfiques
Autor corporatiu: SpringerLink (Online service)
Altres autors: Wang, Feng (Editor)
Sumari:XVIII, 396 p. 88 illus., 9 illus. in color.
text
Idioma:anglès
Publicat: Totowa, NJ : Humana Press : Imprint: Humana, 2008.
Edició:1st ed. 2008.
Col·lecció:Methods in Pharmacology and Toxicology,
Matèries:
Accés en línia:https://doi.org/10.1007/978-1-59745-463-6
Format: Electrònic eBook
Taula de continguts:
  • Biomarker Sample Collection and Handling in the Clinical Setting to Support Early-Phase Drug Development
  • Gene Expression-Based Biomarkers of Drug Safety
  • Profiling Gene Expression Signatures Using Fluorescent Microspheres
  • Real-Time Polymerase Chain Reaction Gene Expression Assays in Biomarker Discovery and Validation
  • SAGE Analysis in Identifying Phenotype Single Nucleotide Polymorphisms
  • Single Nucleotide Polymorphisms and DNA Methylation Analysis Using Pyrosequencing Methods
  • The Application of Laser Capture Microdissection for the Analysis of Cell-Type-Specific Gene Expression in a Complex Tissue:
  • The Use of Two-Dimensional Gel Electrophoresis for Plasma Biomarker Discovery
  • Difference In-Gel Electrophoresis: A High-Resolution Protein Biomarker Research Tool
  • Label-Free Mass Spectrometry-Based Protein Quantification Technologies in Protein Biomarker Discovery
  • Top-Down Quantitative Proteomic Analysis Using a Highly Multiplexed Isobaric Mass Tagging Strategy
  • SELDI Technology for Identification of Protein Biomarkers
  • Sandwich ELISA Microarrays: Generating Reliable and Reproducible Assays for High-Throughput Screens
  • LC-MS Metabonomics Methodology in Biomarker Discovery
  • GC-MS-Based Metabolomics
  • NMR-Based Metabolomics for Biomarker Discovery
  • Unraveling Glycerophospholipidomes by Lipidomics.