Progranulin Methods and Protocols /

书目详细资料
企业作者: SpringerLink (Online service)
其他作者: Bateman, Andrew (Editor), Bennett, Hugh P.J (Editor), Cheung, Siu Tim (Editor)
总结:XIII, 363 p. 79 illus., 56 illus. in color.
text
语言:英语
出版: New York, NY : Springer New York : Imprint: Humana, 2018.
版:1st ed. 2018.
丛编:Methods in Molecular Biology, 1806
主题:
在线阅读:https://doi.org/10.1007/978-1-4939-8559-3
格式: 电子 图书
书本目录:
  • A Brief Overview of Progranulin in Health and Disease
  • Chromatographic Methods for the Purification of Granulin Peptides
  • Methods for Expression and Purification of Biologically Active Recombinant Progranulin
  • Large-Scale Generation of Recombinant Granulin Peptides in E. coli
  • Nuclear Magnetic Resonance Spectroscopy in Analysis of Granulin Three-Dimensional Structure and Cysteine Bridging
  • Data Mining: Applying the AD&FTD Mutation Database to Progranulin
  • Measurement of Circulating Progranulin (PGRN/GP88/GEP) by Enzyme-Linked Immunosorbent Assay and Application in Human Diseases
  • Immunohistochemical Detection of Progranulin (PGRN/GP88/GEP) in Tumor Tissues as a Cancer Prognostic Biomarker
  • Analysis of Progranulin-Mediated Akt and MAPK Activation
  • Mouse Monoclonal Antibodies Against Progranulin (PGRN/GEP) as Therapeutics in Preclinical Cancer Models
  • Methods to Analyze the Role of Progranulin (PGRN/GEP) on Cancer Stem Cell Features
  • Methods to Study the Role of Progranulin in the Tumor Microenvironment
  • Methods to Investigate the Molecular Basis of Progranulin Action on Neurons In Vivo using Caenorhabditis elegans
  • The Use of Caenorhabditis elegans to Study Progranulin in the Regulation of Programmed Cell Death and Stress Response
  • Application of Zebrafish and Knockdown Technology to Define Progranulin Neuronal Function
  • Methods to Investigate the Molecular Basis of Progranulin Actions on Brain and Behavior In Vivo Using Knockout Mice
  • Methods to Investigate the Protection Againts Neurodegenerative Disorders Provided by Progranulin Gene Transfer in the Brain
  • The Interaction between Progranulin with Sortilin and the Lysosome
  • Methods to Study the Role of Progranulin in Preimplanatation Mouse Embryo Development
  • Establishment of a Modified Collagen-Induced Arthritis Mouse Model to Investigate the Anti-Inflammatory Activity of Progranulinin Inflammatory Arthritis
  • Methods for Studying the Function of Progranulin in Atherosclerosis using Both Knockout Mice Models and In Vitro Studies
  • Methods to Investigate the Roles of Prgranulin in Angiogenesis Using In Vitro Strategies and Transgenic Mouse Models.