Immunotoxicity Testing Methods and Protocols /

Podrobná bibliografie
Korporativní autor: SpringerLink (Online service)
Další autoři: DeWitt, Jamie C. (Editor), Rockwell, Cheryl E. (Editor), Bowman, Christal C. (Editor)
Shrnutí:XIII, 412 p. 41 illus., 23 illus. in color.
text
Jazyk:angličtina
Vydáno: New York, NY : Springer New York : Imprint: Humana, 2018.
Vydání:2nd ed. 2018.
Edice:Methods in Molecular Biology, 1803
Témata:
On-line přístup:https://doi.org/10.1007/978-1-4939-8549-4
Médium: Elektronický zdroj Kniha
Obsah:
  • Immunotoxicology: A Brief History
  • Clinical Immunotoxicology
  • Investigative Immunotoxicology
  • Developmental Immunotoxicity (DIT) Testing: Current Recommendations and the Future of DIT Testing
  • Markers of Inflammation
  • The Sheep Erythrocyte T-Dependent Antibody Response (TDAR)
  • Methylated-Bovine Serum Albumin (mBSA)-Induced Delayed-Type Hypersensitivity in Mice
  • Use of the LLNA:BrdU-ELISA for Skin Sensitization Hazard Assessment
  • Host Resistance Assays
  • Enhanced Histopathology Evaluation of Lymphoid Organs
  • Tumor Challenges in Immunotoxicity Testing
  • Flow Cytometry for the Immunotoxicologist
  • Evaluation of Cell-Mediated Immune Function Using the Cytotoxic T Lymphocyte Assay
  • Evaluation of Cell Proliferation and Apoptosis in Immunotoxicity Testing
  • Natural Killer (NK) Cell Assays in Immunotoxicity Testing
  • Dendritic Cell Assays
  • Evaluating Macrophages in Immunotoxicity Testing
  • Evaluating Cytokines in Immunotoxicity Testing
  • Functional Assays of Hematopoietic Stem Cellsin Toxicology Research
  • CD4+ T Cell Differentiation and Activation
  • Isolation and Identification of Innate Lymphoid Cells (ILCs) for Immunotoxicity Testing
  • Evaluating Antigen-Specific IgE Using the Rat Basophil Leukemia Cell (RBL) Assay
  • Challenges for Integrating Immunotoxicology into the 21st Century Toxicology Testing Paradigm.