Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols /
| مؤلف مشترك: | |
|---|---|
| مؤلفون آخرون: | , , |
| الملخص: | X, 227 p. 42 illus., 22 illus. in color. text |
| اللغة: | الإنجليزية |
| منشور في: |
New York, NY :
Springer New York : Imprint: Humana,
2016.
|
| الطبعة: | 1st ed. 2016. |
| سلاسل: | Methods in Molecular Biology,
1336 |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1007/978-1-4939-2926-9 |
| التنسيق: | الكتروني كتاب |
جدول المحتويات:
- Immunoprecipitation of CDK-Cyclin Complexes for Determination of Kinase Activity
- Expression and Purification of Recombinant Cyclins and CDKs for Activity Evaluation
- Expression and Purification of Recombinant CDKs: CDK7, CDK8 and CDK9
- Preparation of CDK/Cyclin Inhibitor Complexes for Structural Determination
- Fragment-Based De Novo Design of Cyclin-Dependent Kinase 2 Inhibitors
- Protein-Protein Interaction Inspire the De Novo Design of Cyclin-Dependent Kinases Peptide Inhibitors
- Identification of Cyclin A Binders with a Fluorescent Peptide Sensor
- Cell Synchronization Techniques to Study the Action of CDK Inhibitors
- Analysis of CDK Inhibitors Action on Mitochondria-Mediated Apoptosis
- Evaluating the Effects of CDK Inhibitors in Ischemia-Reperfusion Injury Models
- Assessing Cell Cycle Independent Function of the CDK Inhibitor p21CDKN1A in DNA Repair
- Drug Delivery Strategies of Chemical CDK Inhibitors
- Animal Models for Studying the In Vivo Functions of Cell Cycle CDKs
- Evaluating Chemical CDK Inhibitors as Cell Death Inducers
- Models for the Study of the Crosstalk between Inflammation and Cell Cycle
- Metabolomic Applications to the Characterization of the Mode-of-Action of CDK Inhibitors.