Chemical Biology Methods and Protocols /

Bibliografske podrobnosti
Korporativna značnica: SpringerLink (Online service)
Drugi avtorji: Hempel, Jonathan E. (Editor), Williams, Charles H. (Editor), Hong, Charles C. (Editor)
Izvleček:XIV, 333 p. 65 illus., 40 illus. in color.
text
Jezik:angleščina
Izdano: New York, NY : Springer New York : Imprint: Humana, 2015.
Izdaja:1st ed. 2015.
Serija:Methods in Molecular Biology, 1263
Teme:
Online dostop:https://doi.org/10.1007/978-1-4939-2269-7
Format: Elektronski Knjiga
Kazalo:
  • Identification of Therapeutic Small Molecule Leads in Cultured Cells Using Multiplexed Pathway Reporter Read-outs
  • Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles
  • Construction and Application of a Photo-cross-linked Chemical Array
  • High Content Screening for Modulators of Cardiac Differentiation in Human Pluripotent Stem Cells
  • Small Molecule High-Throughput Screening Utilizing Xenopus Egg Extract
  • Fission Yeast-based High-throughput Screens for PKA Pathway Inhibitors and Activators
  • A Method for High-throughput Analysis of Chronological Aging in Schizosaccharomyces pombe
  • Protocols for the Routine Screening of Drug Sensitivity in the Human Parasite Trichomonas vaginalis
  • Chemical Genetic Screens Using Arabidopsis thaliana Seedlings Grown on Solid Medium
  • Small Molecule Screening Using Drosophila Models of Human Neurological Disorders
  • High-throughput Small Molecule Screening in Caenorhabditis elegans
  • Whole-organism Screening for Modulators of Fasting Metabolism Using Transgenic Zebrafish
  • High Content Screening for Modulators of Cardiovascular or Global Developmental Pathways in Zebrafish
  • Extraction Methods of Natural Products from Traditional Chinese Medicines
  • Bioassay-guided Identification of Bioactive Molecules from Traditional Chinese Medicines
  • NMR Screening in Fragment-Based Drug Design: A Practical Guide
  • Practical Strategies for Small Molecule Probe Development in Chemical Biology
  • Principal Component Analysis as a Tool for Library Design: A Case Study Investigating Natural Products, Brand-name Drugs, Natural Product-like Libraries, and Drug-like Libraries
  • Small Molecule Library Screening by Docking with PyRx
  • Fluorous Photoaffinity Labeling to Probe Protein-Small Molecule Interactions
  • Identification of the Targets of Biologically Active Small Molecules Using Quantitative Proteomics
  • Drug Affinity Responsive Target Stability (DARTS) for Small Molecule Target Identification
  • Chemical Genomic Profiling via Barcode Sequencing to Predict Compound Mode of Action
  • Image-Based Prediction of Drug Target in Yeast.