Rhinovirus Methods and Protocols /

Podrobná bibliografie
Korporativní autor: SpringerLink (Online service)
Další autoři: Sajjan, Umadevi (Editor)
Shrnutí:X, 194 p. 48 illus., 43 illus. in color.
text
Jazyk:angličtina
Vydáno: New York, NY : Springer US : Imprint: Humana, 2025.
Vydání:1st ed. 2025.
Edice:Methods in Molecular Biology, 2903
Témata:
On-line přístup:https://doi.org/10.1007/978-1-0716-4410-2
Médium: Elektronický zdroj Kniha
Obsah:
  • Detection of virus in clinical samples by PCR
  • Laboratory protocol for propagation and purification of rhinovirus A and B suitable for in vitro and in vivo infection
  • Method to generate high-titre rhinovirus C for in vitro and in vivo studies
  • Quantification of infectious rhinovirus A and B by plaque assay
  • Quantifying Rhinovirus Genomic and Negative-Strand RNA by RT-PCR
  • Determination of binding and endocytosis of rhinovirus by flow cytometry
  • Assessment of viral replication in rhinovirus-infected airway epithelial cells
  • Analysis of adherence junctions in rhinovirus-infected airway epithelial cells
  • Culturing of airway stem cells obtained from COPD and asthma patients to assess the effects of rhinovirus infection
  • Investigation of Differentiated Nasal Epithelial Responses to Infection with Clinical Isolates of Rhinovirus A and C
  • In vivo model to assess the nasal infection by minor group rhinovirus
  • Identification and function of type 2 innate lymphoid cells in rhinovirus-infected mouse model of asthma
  • Assessment of rhinovirus infection in a mouse model of COPD
  • Infection of immature mice with rhinovirus for the study of asthma pathogenesis
  • In vitro model to test therapeutic agents against rhinovirus.