Chemogenomics Methods and Protocols /
| Tác giả của công ty: | |
|---|---|
| Tác giả khác: | , |
| Tóm tắt: | XI, 234 p. 62 illus., 60 illus. in color. text |
| Ngôn ngữ: | Tiếng Anh |
| Được phát hành: |
New York, NY :
Springer US : Imprint: Humana,
2023.
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| Phiên bản: | 1st ed. 2023. |
| Loạt: | Methods in Molecular Biology,
2706 |
| Những chủ đề: | |
| Truy cập trực tuyến: | https://doi.org/10.1007/978-1-0716-3397-7 |
| Định dạng: | Điện tử Sách |
Mục lục:
- An Introduction to Chemogenomics
- Developing a Kinase Chemogenomic Set: Facilitating Investigation into Kinase Biology by Linking Phenotypes to Targets
- Compilation of Custom Compound/Bioactivity Datasets from Public Repositories
- Quality Control of Chemogenomic Library using LC-MS
- Annotation of the Effect of Chemogenomic Compounds on Cell Health using High-Content Microscopy in Live-Cell Mode
- Characterization of Cellular Viability using Label-Free Brightfield Live-Cell Imaging
- Plate-Based Screening for DUB Inhibitors
- NanoBRET™ Live Cell Kinase Selectivity Profiling Adapted for High Throughput Screening
- A Fluorescence-Based Reporter Gene Assay to Characterize Nuclear Receptor Modulators
- Measuring Protein-Protein Interactions in Cells using NanoLuciferase Bioluminescence Resonance Energy Transfer (NanoBRET) Assay
- HiBiT Cellular Thermal Shift Assay (HiBiT CETSA)
- Detection of Cellular Target Engagement for Small Molecule Modulators of Striatal-Enriched Protein Tyrosine Phosphatase (STEP)
- Target Deconvolution by Limited Proteolysis Coupled to Mass Spectrometry
- Global Assessment of Drug Target Engagement and Selectivity of Covalent Cysteine-Reactive Inhibitors using Alkyne-Functionalized Probes
- 3D-Spheroid Invasion Assay for High-Throughput Screening of Small Molecule Libraries
- Live-Cell High-Throughput Screen for Monitoring Autophagy Flux
- Phenotypic Chemical Screening in CD4+ T Cells to Identify Epigenetic Inhibitors.