Cancer Systems and Integrative Biology

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Outros autores: Kasid, Usha N. (Editor), Clarke, Robert (Editor)
Summary:XIII, 375 p. 1 illus.
text
Idioma:inglés
Publicado: New York, NY : Springer US : Imprint: Humana, 2023.
Edición:1st ed. 2023.
Series:Methods in Molecular Biology, 2660
Subjects:
Acceso en liña:https://doi.org/10.1007/978-1-0716-3163-8
Formato: Electrónico Libro
Table of Contents:
  • Introduction: Cancer Systems and Integrative Biology
  • Genome-Wide Analysis of Palindrome Formation with Next-Generation Sequencing (GAPF-Seq) and a Bioinformatics Pipeline for Assessing De Novo Palindromes in Cancer Genomes
  • Sample Preparation and Differential Gene Expression Analysis of Human Cancer Cell Lines by RNA Sequencing
  • Generating Mitochondrial-Nuclear Exchange (MNX) Mice to Identify Mitochondrial Determinants of Cancer Metastasis
  • 3D Autologous Culture Method for Precision Oncology
  • High-Plex Spatial Profiling of RNA and Protein Using Digital Spatial Profiler
  • Integration of Single Cell RNA-Sequencing and Network Analysis to Investigate Mechanism of Drug Resistance
  • Combination of Tissue Microarray Profiling and Multiplexed IHC Approaches to Investigate Transport Mechanism of Nucleoside Analog Drug Resistance
  • In Situ Proximity Ligation Assay to Visualize Protein-Protein Interactions in Tumor Specimens
  • Integration of Metabolomic and Proteomic Data to Uncover Actionable Metabolic Pathways
  • Linking Expression of Cell-Surface Receptors with Transcription Factors by Computational Analysis of Paired Single-Cell Proteomes and Transcriptomes
  • Mass Spectrometry-Based Tissue Imaging of the Tumor Microenvironment
  • Multiplexed Immunoassay Using Quantum Dots to Monitor Proteins Secreted from Single Cells at Near-Single Molecule Resolution
  • Isolation and Identification of Plasma Extracellular Vesicles Protein Biomarkers
  • Discovery of a Hidden Proinflammatory Signaling Proteome Using a Large Scale, Targeted Antibody Microarray Platform
  • Multiplex Fluorescent Immunohistochemistry for Preservation of Tumor Microenvironment Architecture and Spatial Relationship of Cells in Tumor Tissues
  • Circle Damage Sequencing for Whole-Genome Analysis of DNA Damage
  • CRISPR-Directed Gene Editing as a Method to Reduce Chemoresistance in Lung Cancer Cells
  • Integrated In Silico Analysis of Proteogenomics and Drug Targets for Pancreatic Cancer Survival
  • Advanced Computational Methods to Evaluate Vascular Heterogeneity in Tumor Tissue Based on Single Plane Illumination Microscopy
  • Illuminating DEPDC1B in Multi-Pronged Regulation of Tumor Progression
  • Single Cell and Spatial Analysis of Emergent Organoid Platforms
  • Analysis of Phase-Separated Biomolecular Condensates in Cancer
  • Gain-of-Function Variomics and Multi-Omics Network Biology for Precision Medicine.