Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy

Podrobná bibliografie
Korporativní autor: SpringerLink (Online service)
Další autoři: Vohora, Divya (Editor)
Shrnutí:XIV, 250 p. 37 illus., 24 illus. in color.
text
Jazyk:angličtina
Vydáno: New York, NY : Springer US : Imprint: Humana, 2021.
Vydání:1st ed. 2021.
Edice:Neuromethods, 167
Témata:
On-line přístup:https://doi.org/10.1007/978-1-0716-1254-5
Médium: Elektronický zdroj Kniha
Obsah:
  • Models of Seizures and Epilepsy: Important Tools in the Discovery and Evaluation of Novel Epilepsy Therapies
  • Protocol for Rodent Organotypic Hippocampal Slice Culture Model for Ex Vivo Monitoring of Epileptogenesis
  • Methods for the Screening of New Chemical Entities for Deciphering Neuroinflammatory and Associated Pathways in Seizures: An In Vitro Perspective
  • Cellular Electrophysiological Methods to Decipher the Altered Synaptic Transmission Associated with Drug Resistant Epilepsy
  • Acute Seizure Tests Used in Epilepsy Research: Step-by-Step Protocol of the Maximal Electroshock Seizure (MES) Test, The Maximal Electroshock Seizure Threshold (MEST) Test, and the Pentylenetetrazole (PTZ)-Induced Seizure Test in Rodents
  • Procedures for Electrical and Chemical Kindling Models in Rats and Mice
  • Methods for the Induction of status epilepticus and Temporal Lobe Epilepsy in Rodents: The Kainic Acid and the Pilocarpine Model
  • Seizure Monitoring inRodents
  • Protocol for 6Hz Corneal Stimulation in Rodents for Refractory Seizures
  • A Method to Induce Lamotrigine-Resistant Corneal Kindled Mice
  • Protocol for Drug Screening with Quantitative Video-Electroencephalography in a Translational Model of Refractory Neonatal Seizures
  • Methods to Investigate Seizures and Associated Cognitive Decline using Zebrafish Model
  • C. elegans as a Potential Model for Acute Seizure-Like Activity.