Chimeric Antigen Receptor T Cells Development and Production /

書目詳細資料
企業作者: SpringerLink (Online service)
其他作者: Swiech, Kamilla (Editor), Malmegrim, Kelen Cristina Ribeiro (Editor), Picanço-Castro, Virgínia (Editor)
總結:XI, 274 p. 29 illus., 25 illus. in color.
text
語言:英语
出版: New York, NY : Springer US : Imprint: Humana, 2020.
版:1st ed. 2020.
叢編:Methods in Molecular Biology, 2086
主題:
在線閱讀:https://doi.org/10.1007/978-1-0716-0146-4
格式: 電子 電子書
書本目錄:
  • CAR-T Cells for Cancer Treatment: Current Design and Next Frontiers
  • Selection of Antibody Fragments for CAR-T Cell Therapy from Phage Display Libraries
  • Phase I/II Manufacture of Lentiviral Vectors under GMP in an Academic Setting
  • Production of Lentivirus for the Establishment of CAR-T Cells
  • Optimized Production of Lentiviral Vectors for CAR-T Cell
  • Lentiviral Vectors Production in Suspension Culture Using Serum-Free Medium for the Transduction of CAR-T Cells
  • In vitro Transcribed (IVT)-mRNA CAR Therapy Development
  • Generation of Chimeric Antigen Receptor T Cells Using Gammaretroviral Vectors
  • Generation of CAR+ T Lymphocytes using the Sleeping Beauty Transposon System
  • Platforms for Clinical-grade Car-T Cell Expansion
  • CAR-T Cell Expansion in a Xuri Cell Expansion System W25
  • Methods and Process Optimization for Large Scale CAR T Expansion Using the G-Rex Cell Culture Platform
  • Replication Competent LentivirusAnalysis of Vector Transduced T Cell Products used in Cancer Immunotherapy Clinical Trials
  • Immunophenotypic Analysis of CAR-T Cells
  • Approaches of T Cell Activation and Differentiation for CAR-T Cell Therapies
  • Determination of Cytotoxic Potential of CAR-T Cells in Co-cultivation Assays
  • Analysis of CAR-mediated Tonic Signaling
  • Generation of Tumor Cells Expressing Firefly Luciferase (fLuc) to Evaluate the Effectiveness of CAR in a Murine Model
  • Analysis of Antitumor Effects of CAR-T Cells in Mice with Solid Tumors.