Chimeric Antigen Receptor T Cells Development and Production /
| Corporate Author: | |
|---|---|
| Other Authors: | , , |
| Summary: | XI, 274 p. 29 illus., 25 illus. in color. text |
| Language: | English |
| Published: |
New York, NY :
Springer US : Imprint: Humana,
2020.
|
| Edition: | 1st ed. 2020. |
| Series: | Methods in Molecular Biology,
2086 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-1-0716-0146-4 |
| Format: | Electronic eBook |
Table of Contents:
- CAR-T Cells for Cancer Treatment: Current Design and Next Frontiers
- Selection of Antibody Fragments for CAR-T Cell Therapy from Phage Display Libraries
- Phase I/II Manufacture of Lentiviral Vectors under GMP in an Academic Setting
- Production of Lentivirus for the Establishment of CAR-T Cells
- Optimized Production of Lentiviral Vectors for CAR-T Cell
- Lentiviral Vectors Production in Suspension Culture Using Serum-Free Medium for the Transduction of CAR-T Cells
- In vitro Transcribed (IVT)-mRNA CAR Therapy Development
- Generation of Chimeric Antigen Receptor T Cells Using Gammaretroviral Vectors
- Generation of CAR+ T Lymphocytes using the Sleeping Beauty Transposon System
- Platforms for Clinical-grade Car-T Cell Expansion
- CAR-T Cell Expansion in a Xuri Cell Expansion System W25
- Methods and Process Optimization for Large Scale CAR T Expansion Using the G-Rex Cell Culture Platform
- Replication Competent LentivirusAnalysis of Vector Transduced T Cell Products used in Cancer Immunotherapy Clinical Trials
- Immunophenotypic Analysis of CAR-T Cells
- Approaches of T Cell Activation and Differentiation for CAR-T Cell Therapies
- Determination of Cytotoxic Potential of CAR-T Cells in Co-cultivation Assays
- Analysis of CAR-mediated Tonic Signaling
- Generation of Tumor Cells Expressing Firefly Luciferase (fLuc) to Evaluate the Effectiveness of CAR in a Murine Model
- Analysis of Antitumor Effects of CAR-T Cells in Mice with Solid Tumors.