Effect of argon and nitrogen mixing ratios on the properties of the coatings deposited via reactive magnetron sputtering of a hydroxyapatite target; Applied Surface Science; Vol. 726

Effect of argon and nitrogen mixing ratios on the properties of the coatings deposited via reactive magnetron sputtering of a hydroxyapatite target; Applied Surface Science; Vol. 726

書誌詳細
Parent link:Applied Surface Science.— .— Amsterdam: Elsevier Science Publishing Company Inc.
Vol. 726.— 2026.— Article number 165972, 17 p.
その他の著者: Kozelskaya A. I. Anna Ivanovna, Marjin (Maryin) P. V. Pavel Vladimirovich, Sosnina A. V. Alyona Viktorovna, Rutkowski S. Sven, Shugurov A. R. Artur Rubinovich, Zhukov Yu. M. Yuriy Mikhaylovich, Tran Hoang T., Bukal V. R. Vladislav Romanovich, Akimchenko I. O. Igor Olegovich, Nasibov T. N. Temir Nadirovich, Gorokhova A. V. Anna Viktorovna, Khlusov I. A. Igor Albertovich, Litvinova L. S. Larisa Sergeevna, Khaziakhmatova O. G. Olga Gennadjevna, Malashchenko V. I. Vladimir Vladimirovich
要約:Title screen
There is no publication in the scientific literature describing nitrogen oxide-containing calcium phosphate coatings deposited by magnetron sputtering. It can be assumed that sputtering of hydroxyapatite in a nitrogen-rich atmosphere facilitates the formation of coatings containing nitrogen oxide compounds. The presence of nitrogen oxide compounds in calcium phosphate coatings may have a positive effect on angiogenesis, stimulate local metabolism and improve the bioactivity of the coated implants. In this study, calcium phosphate coatings were deposited on titanium substrates via reactive magnetron sputtering of a hydroxyapatite target using different nitrogen-argon gas mixtures: 100% nitrogen, 75% nitrogen: 25% argon, 50% nitrogen: 50% argon, 25% nitrogen: 75% argon and 100% argon. The surface morphology, mechanical properties, wettability, chemical composition, and in vitro biological properties of the coatings were investigated. The results indicate that the coating thickness increases with the Ar content. Furthermore, the coatings produced via hydroxyapatite sputtering in pure argon were denser and demonstrated greater hardness than those deposited in pure nitrogen. An analysis revealed that the coatings are characterized by the formation of N–C and N–O bonds. Exposure to N–O and N–C enriched coatings downregulated ALPL and BMP2 genes in MSCs after 7 days; nevertheless, the BMP2 differentiation pathway was preserved
Текстовый файл
AM_Agreement
言語:英語
出版事項: 2026
主題:
Hydroxyapatite
Reactive magnetron sputtering
Calcium phosphate coatings
Nitrogen oxide
Mesenchymal stromal/stem cell
In vitro study
электронный ресурс
труды учёных ТПУ
オンライン･アクセス:https://doi.org/10.1016/j.apsusc.2026.165972
フォーマット: 電子媒体 図書の章
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=685416

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