Effect of argon and nitrogen mixing ratios on the properties of the coatings deposited via reactive magnetron sputtering of a hydroxyapatite target; Applied Surface Science; Vol. 726
| Parent link: | Applied Surface Science.— .— Amsterdam: Elsevier Science Publishing Company Inc. Vol. 726.— 2026.— Article number 165972, 17 p. |
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| Další autoři: | , , , , , , , , , , , , , , |
| Shrnutí: | Title screen There is no publication in the scientific literature describing nitrogen oxide-containing calcium phosphate coatings deposited by magnetron sputtering. It can be assumed that sputtering of hydroxyapatite in a nitrogen-rich atmosphere facilitates the formation of coatings containing nitrogen oxide compounds. The presence of nitrogen oxide compounds in calcium phosphate coatings may have a positive effect on angiogenesis, stimulate local metabolism and improve the bioactivity of the coated implants. In this study, calcium phosphate coatings were deposited on titanium substrates via reactive magnetron sputtering of a hydroxyapatite target using different nitrogen-argon gas mixtures: 100% nitrogen, 75% nitrogen: 25% argon, 50% nitrogen: 50% argon, 25% nitrogen: 75% argon and 100% argon. The surface morphology, mechanical properties, wettability, chemical composition, and in vitro biological properties of the coatings were investigated. The results indicate that the coating thickness increases with the Ar content. Furthermore, the coatings produced via hydroxyapatite sputtering in pure argon were denser and demonstrated greater hardness than those deposited in pure nitrogen. An analysis revealed that the coatings are characterized by the formation of N–C and N–O bonds. Exposure to N–O and N–C enriched coatings downregulated ALPL and BMP2 genes in MSCs after 7 days; nevertheless, the BMP2 differentiation pathway was preserved Текстовый файл AM_Agreement |
| Jazyk: | angličtina |
| Vydáno: |
2026
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| Témata: | |
| On-line přístup: | https://doi.org/10.1016/j.apsusc.2026.165972 |
| Médium: | Elektronický zdroj Kapitola |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=685416 |