Anisotropic nanorod-integrated magneto-mechano-electric cascade system for neural electrical stimulation; Acta Biomaterialia; Vol. 209

Anisotropic nanorod-integrated magneto-mechano-electric cascade system for neural electrical stimulation

Bibliographic Details
Parent link:Acta Biomaterialia.— .— Amsterdam: Elsevier Science Publishing Company Inc.
Vol. 209.— 2026.— P. 452-465
Other Authors: Dan Wei, Xurui Zhao, Mingze Zeng, Li Rong, Zhang Wei, Urakova A. O. Alina Olegovna, Jie Ding, Wu Chengheng, Sun Jing, Chernozem R. V. Roman Viktorovich, Fan Hongsong
Summary:Title screen
Piezoelectric materials are now being considered as a potential treatment system for neural electrical stimulation. However, their therapeutic efficacy is limited by insufficient electrical outputs, which are generated by cellular forces and/or tissue motions. Herein, we constructed a high-efficiency magneto-mechano-electric cascade system with magnetic field (MF)-driven wireless electrical stimulation. The anisotropic Fe3O4 nanorod (RFO)-integrated poly(vinylidene fluoride-co-trifluoroethylene) copolymer (PVDF-TrFE) fibrous scaffold (PT-RFO) with enhanced piezoelectric β-phase content was prepared via electrospinning technique. Under a remote pulsed MF, the high-efficiency electrical outputs within PT-RFO scaffold could be generated by converting pressure force and deflection force within the contact interface between anisotropic RFO and PVDF-TrFE matrix. As a result, such PT-RFO scaffold could accelerate the repair of injured sciatic nerves and promote the recovery of damaged motor functions in rat models. This work highlights the potential application of a wireless controllable cascade stimulation system integrated multiple designable cues for neural repair and modulation
Текстовый файл
AM_Agreement
Language:English
Published: 2026
Subjects:
Biomaterials
Piezoelectric materials
Anisotropic nanorod
Magneto-mechano-electric cascade
Neural electrical stimulation
электронный ресурс
труды учёных ТПУ
Online Access:https://doi.org/10.1016/j.actbio.2025.11.007
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=685366

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