Anisotropic nanorod-integrated magneto-mechano-electric cascade system for neural electrical stimulation
| Parent link: | Acta Biomaterialia.— .— Amsterdam: Elsevier Science Publishing Company Inc. Vol. 209.— 2026.— P. 452-465 |
|---|---|
| Other Authors: | , , , , , , , , , , |
| Summary: | Title screen Piezoelectric materials are now being considered as a potential treatment system for neural electrical stimulation. However, their therapeutic efficacy is limited by insufficient electrical outputs, which are generated by cellular forces and/or tissue motions. Herein, we constructed a high-efficiency magneto-mechano-electric cascade system with magnetic field (MF)-driven wireless electrical stimulation. The anisotropic Fe3O4 nanorod (RFO)-integrated poly(vinylidene fluoride-co-trifluoroethylene) copolymer (PVDF-TrFE) fibrous scaffold (PT-RFO) with enhanced piezoelectric β-phase content was prepared via electrospinning technique. Under a remote pulsed MF, the high-efficiency electrical outputs within PT-RFO scaffold could be generated by converting pressure force and deflection force within the contact interface between anisotropic RFO and PVDF-TrFE matrix. As a result, such PT-RFO scaffold could accelerate the repair of injured sciatic nerves and promote the recovery of damaged motor functions in rat models. This work highlights the potential application of a wireless controllable cascade stimulation system integrated multiple designable cues for neural repair and modulation Текстовый файл AM_Agreement |
| Language: | English |
| Published: |
2026
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| Subjects: | |
| Online Access: | https://doi.org/10.1016/j.actbio.2025.11.007 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=685366 |
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| 300 | |a Title screen | ||
| 320 | |a References: 56 tit | ||
| 330 | |a Piezoelectric materials are now being considered as a potential treatment system for neural electrical stimulation. However, their therapeutic efficacy is limited by insufficient electrical outputs, which are generated by cellular forces and/or tissue motions. Herein, we constructed a high-efficiency magneto-mechano-electric cascade system with magnetic field (MF)-driven wireless electrical stimulation. The anisotropic Fe3O4 nanorod (RFO)-integrated poly(vinylidene fluoride-co-trifluoroethylene) copolymer (PVDF-TrFE) fibrous scaffold (PT-RFO) with enhanced piezoelectric β-phase content was prepared via electrospinning technique. Under a remote pulsed MF, the high-efficiency electrical outputs within PT-RFO scaffold could be generated by converting pressure force and deflection force within the contact interface between anisotropic RFO and PVDF-TrFE matrix. As a result, such PT-RFO scaffold could accelerate the repair of injured sciatic nerves and promote the recovery of damaged motor functions in rat models. This work highlights the potential application of a wireless controllable cascade stimulation system integrated multiple designable cues for neural repair and modulation | ||
| 336 | |a Текстовый файл | ||
| 371 | 0 | |a AM_Agreement | |
| 461 | 1 | |t Acta Biomaterialia |c Amsterdam |n Elsevier Science Publishing Company Inc. | |
| 463 | 1 | |t Vol. 209 |v P. 452-465 |d 2026 | |
| 610 | 1 | |a Biomaterials | |
| 610 | 1 | |a Piezoelectric materials | |
| 610 | 1 | |a Anisotropic nanorod | |
| 610 | 1 | |a Magneto-mechano-electric cascade | |
| 610 | 1 | |a Neural electrical stimulation | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 701 | 0 | |a Dan Wei | |
| 701 | 0 | |a Xurui Zhao | |
| 701 | 0 | |a Mingze Zeng | |
| 701 | 0 | |a Li Rong | |
| 701 | 0 | |a Zhang Wei | |
| 701 | 1 | |a Urakova |b A. O. |c specialist in the field of material science |c Laboratory assistant of Tomsk Polytechnic University |f 2002- |g Alina Olegovna |9 88596 | |
| 701 | 0 | |a Jie Ding | |
| 701 | 0 | |a Wu Chengheng | |
| 701 | 0 | |a Sun Jing | |
| 701 | 1 | |a Chernozem |b R. V. |c physicist |c Associate Professor of Tomsk Polytechnic University |f 1992- |g Roman Viktorovich |9 19499 | |
| 701 | 0 | |a Fan Hongsong | |
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