Antibacterial and biocompatible Zn and Cu containing CaP magnetron coatings for MgCa alloy functionalization; Journal of Materials Research and Technology; Vol. 25

Antibacterial and biocompatible Zn and Cu containing CaP magnetron coatings for MgCa alloy functionalization; Journal of Materials Research and Technology; Vol. 25

מידע ביבליוגרפי
Parent link:Journal of Materials Research and Technology.— .— Amsterdam: Elsevier Science Publishing Company Inc.
Vol. 25.— 2023.— P. 2177-2203
מחברים אחרים: Prosolov K. A. Konstantin Aleksandrovich, Luginin N. A. Nikita Andreevich, Litvinova L. S. Larisa Sergeevna, Fedorov M. A. Maksim Aleksandrovich, Anisenya I. I. Iljya Ivanovich, Mushtovatova L. S. Lyudmila Stepanovna, Snetkov A. A. Aleksandr Andreevich, Bukharov A. V. Artem Viktorovich, Khlusov I. A. Igor Albertovich, Sharkeev Yu. P. Yury Petrovich
סיכום:Title screen
The application of bioresorbable magnesium-based alloys in medical implants has been limited by their rapid dissolution rate. In order to enhance their suitability for medical use, this study proposes the deposition of calcium phosphate (CaP) onto Mg (0.8) Ca alloy using an RF magnetron sputtering with stoichiometric hydroxyapatite and Zn- or Cu-substituted hydroxyapatites. The comparison study assessed structure, composition, and mechanical properties of Mg (0.8) Ca alloy, Zn, and Cu containing CaP coatings. CaP coatings showed an increased Ca/P ratio due to re-sputtering. Sputtering of Zn- and Cu-substituted hydroxyapatites resulted in CaP dopant concentrations of 0.6 ± 0.2 wt% and 0.4 ± 0.1 wt%, respectively. All deposited coatings were found to be amorphous. Addition of Cu or Zn dopant slightly changed the CaP coatings' scratch resistance, with critical loads of 2.19 ± 0.60 N, 2.55 ± 0.95 N, and 2.76 ± 1.29 N for CaP, Zn–CaP, and Cu–CaP coatings, respectively. CaP coatings reduced corrosion current and increased electrical resistance compared to MgCa samples, but Cu addition accelerated corrosion. Biological tests revealed that the hAMSCs survival was improved and the bacteriostatic effect on the pathogenic SA strain was enhanced for Zn–CaP coatings when compared to CaP and Cu–CaP coatings. These findings suggest that the deposition of CaP coatings onto Mg (0.8) Ca alloy, and particularly the use of Zn-substituted hydroxyapatites, could be a promising approach to enhance the suitability of magnesium-based alloys for medical implant application
Текстовый файл
AM_Agreement
שפה:אנגלית
יצא לאור: 2023
נושאים:
электронный ресурс
труды учёных ТПУ
Biodegradation
Bioactive coatings
Hydroxyapatite
Physical vapor deposition
Antibacterial activity
גישה מקוונת:https://doi.org/10.1016/j.jmrt.2023.06.065
פורמט: אלקטרוני Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=684998

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