Ascorbate induces G2/M arrest and necrosis without generation of direct DNA double-strand breaks

Detalles Bibliográficos
Parent link:	Heliyon.— .— Amsterdam: Elsevier Science Publishing Company Inc. Vol. 11.— 2025.— Article number e43964, 14 p.
Otros Autores:	Hariri M. Mehran, Papalanis E. Eleftherios, Spiegelberg D. Diana, Plotnikov E. V. Evgeny Vladimirovich, Viktorsson K. Kristina, Stenerlow B. Bo
Sumario:	Title screen Ascorbate is used for combination therapy with promising results in clinical trials. The proposed main ascorbate cytotoxic effect is DNA damage induction through excessive oxidative stress. However, the involvement of DNA double-strand breakage (DSB) formation and repair in ascorbate-induced DNA damage remains to be revealed Текстовый файл AM_Agreement
Publicado:	2025
Materias:	Ascorbate DSB NHEJ γH2AX 53BP1 XRCC4 DNA-PKcs cell cycle электронный ресурс труды учёных ТПУ
Acceso en línea:	https://doi.org/10.1016/j.heliyon.2025.e43964
Formato:	Electrónico Capítulo de libro
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=683007

Internet