Конъюгат на основе инвертазы для оценки качества вакцин с помощью персонального глюкометра; Перспективы развития фундаментальных наук; Т. 2 : Химия
| Parent link: | Перспективы развития фундаментальных наук=Prospects of Fundamental Sciences Development: сборник научных трудов XХII Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 22-25 апреля 2025/ Национальный исследовательский Томский политехнический университет ; под ред. И. А. Курзиной [и др.].— .— Томск: Изд-во ТПУ Т. 2 : Химия.— 2025.— С. 130-132 |
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| Outros Autores: | , , |
| Resumo: | Заглавие с экрана Currently, vaccine development requires significant time and financial costs, and their quality assessment requires the use of complex and expensive methods. Enzyme-linked immunosorbent assay (ELISA), while remaining one of the most common vaccine quality control methods, requires a long analysis time and often uses horseradish peroxidase (HRP) as an enzyme label. HRP production is characterized by high cost and low product yield, which stimulates the search for alternative enzyme labels. In this study, a new strategy for synthesizing a conjugate based on invertase and immunoglobulins of class G is proposed. Invertase, which catalyzes the hydrolysis of sucrose to form glucose, allows the use of a personal glucose meter to record the analytical signal. This significantly simplifies and accelerates the process of assessing the quality of immunobiological products, making it more accessible to laboratories with limited resources and for express tests. The aim of the work is to develop a conjugate based on invertase and antibodies in an immunoassay using a glucose meter. The developed method, based on the use of a personal glucose meter, will provide a convenient, fast and cost-effective way to control the quality of vaccines, and will also be potentially suitable for use in various conditions Текстовый файл |
| Idioma: | russo |
| Publicado em: |
2025
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| Assuntos: | |
| Acesso em linha: | http://earchive.tpu.ru/handle/11683/132825 |
| Formato: | Recurso Electrónico Capítulo de Livro |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=682389 |
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| 200 | 1 | |a Конъюгат на основе инвертазы для оценки качества вакцин с помощью персонального глюкометра |d Invertase-based conjugate for vaccine quality assessment using a personal glucose meter |f А. В. Кольцова, Е. И. Михневич, А. Н. Соломоненко |g науч. рук. Е. В. Дорожко |z eng | |
| 300 | |a Заглавие с экрана | ||
| 320 | |a Список литературы: 4 назв | ||
| 330 | |a Currently, vaccine development requires significant time and financial costs, and their quality assessment requires the use of complex and expensive methods. Enzyme-linked immunosorbent assay (ELISA), while remaining one of the most common vaccine quality control methods, requires a long analysis time and often uses horseradish peroxidase (HRP) as an enzyme label. HRP production is characterized by high cost and low product yield, which stimulates the search for alternative enzyme labels. In this study, a new strategy for synthesizing a conjugate based on invertase and immunoglobulins of class G is proposed. Invertase, which catalyzes the hydrolysis of sucrose to form glucose, allows the use of a personal glucose meter to record the analytical signal. This significantly simplifies and accelerates the process of assessing the quality of immunobiological products, making it more accessible to laboratories with limited resources and for express tests. The aim of the work is to develop a conjugate based on invertase and antibodies in an immunoassay using a glucose meter. The developed method, based on the use of a personal glucose meter, will provide a convenient, fast and cost-effective way to control the quality of vaccines, and will also be potentially suitable for use in various conditions | ||
| 336 | |a Текстовый файл | ||
| 461 | 1 | |0 682243 |t Перспективы развития фундаментальных наук |l Prospects of Fundamental Sciences Development |o сборник научных трудов XХII Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 22-25 апреля 2025 |9 682243 |c Томск |n Изд-во ТПУ |f Национальный исследовательский Томский политехнический университет ; под ред. И. А. Курзиной [и др.] | |
| 463 | 1 | |0 682251 |9 682251 |t Т. 2 : Химия |d 2025 |u conference_tpu-2025-C21_V2.pdf |v С. 130-132 |l Vol. 2 : Chemistry | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a invertase | |
| 610 | 1 | |a enzyme immunoassay | |
| 610 | 1 | |a glutaraldehyde | |
| 610 | 1 | |a glucose meter | |
| 610 | 1 | |a hepatitis A virus | |
| 700 | 1 | |a Кольцова |b А. В. |g Алёна Владимировна |f 2003- |c химик |c инженер Томского политехнического университета |9 89093 | |
| 701 | 1 | |a Михневич |b Е. И. | |
| 701 | 1 | |a Соломоненко |b А. Н. |c химик-технолог |c инженер Томского политехнического университета |f 1995- |g Анна Николаевна |9 22490 | |
| 702 | 1 | |a Дорожко |b Е. В. |c химик |c инженер Томского политехнического университета |f 1979- |g Елена Владимировна |4 727 | |
| 801 | 0 | |a RU |b 63413507 |c 20251016 |g RCR | |
| 856 | 4 | |z http://earchive.tpu.ru/handle/11683/132825 |u http://earchive.tpu.ru/handle/11683/132825 | |
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