Conceptual rationale for the use of chemically modified nanocomposites for active influence on atherosclerosis using the greater omentum model of experimental animals

Conceptual rationale for the use of chemically modified nanocomposites for active influence on atherosclerosis using the greater omentum model of experimental animals

Bibliographic Details
Parent link:Nanomedicine: Nanotechnology, Biology and Medicine.— .— Amsterdam: Elsevier Science Publishing Company Inc.
Vol. 62.— 2024.— Article number 102787, 7 p.
Other Authors: Akhmedov Sh. Shamil, Stepanov I. Ivan, Afanasyev S. Sergey, Tverdokhlebov S. I. Sergei Ivanovich, Filimonov V. D. Viktor Dmitrievich, Kamenshchikov N. Nikolay, Yermakov A. Anatoly, Suowen Xu, Afanasyeva N. Natalia, Kozlov B. Boris
Summary:Title screen
The use of chemically modified nanocomposites for atherosclerotic plaques can open up new opportunities for studying their effect on changing the structure of the plaque itself. It was shown on the model of the greater omentum of two groups of experimental animals (rats n = 30), which were implanted with Fe@C NPs nanocomposites of 10–30 Nm size into the omentum area. Group 1 (n = 15) consisted of animals that were implanted with chemically modified Fe@C NPs nanocomposites and control group 2 (n = 15) was with non-modified Fe@C NPs nanocomposites. After 1, 2 and 3 weeks we conducted the morphological study of changes in the structure of the omentum using two dyes (Nile Blue and Sudan III), which are specific for adipose tissue. Chemically modified nanocomposites have demonstrated, in contrast to non-modified nanoparticles, to cause morphological changes in the structure of the greater omentum accompanied by the probable release of a similar antiatherogenic factor
Текстовый файл
AM_Agreement
Language:English
Published: 2024
Subjects:
Atherosclerosis
Atherosclerotic plaque
Nanocomposite
Chemically modified carbon-coated iron nanoparticle
Coronary stent
труды учёных ТПУ
электронный ресурс
Online Access:https://doi.org/10.1016/j.nano.2024.102787
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=681221

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