Integration of Graphene into Calcium Phosphate Coating for Implant Electronics; ACS Applied Materials and Interfaces; Vol. 17, iss. 9

Bibliografiske detaljer
Parent link:ACS Applied Materials and Interfaces.— .— Washington: American Chemical Society
Vol. 17, iss. 9.— 2025.— P. 13527-13537
Andre forfattere: Dogadina Е. М. Elizaveta Maksimovna, Rodriguez (Rodriges) Contreras R. D. Raul David, Fatkullin M. I. Maksim Ilgizovich, Lipovka A. A. Anna Anatolyevna, Kozelskaya A. I. Anna Ivanovna, Averkiev A. A. Andrey Alekseevich, Plotnikov E. V. Evgeny Vladimirovich, Jia Xin, Liu Chaozong, Chen Jin-Ju, Cheng Chong, Que Li, Tverdokhlebov S. I. Sergei Ivanovich, Sheremet E. S. Evgeniya Sergeevna
Summary:Title screen
Bone injuries remain a significant challenge, driving the development of new materials and technologies to enhance healing. This study presents a novel approach for incorporating graphene into calcium phosphate (CaP) coatings on titanium alloy (Ti) substrates, with the aim of creating a new generation of materials for bone implant electronics. The stability of the composite coating under physiological conditions, long-term electrical and mechanical durability, and biocompatibility were systematically investigated. We integrated graphene into the CaP coating through the laser processing of diazonium-functionalized graphene films applied to the surface of CaP-coated Ti. The laser treatment induced several processes, including the removal of aryl groups, the formation of conductive pathways, and chemical bonding with the CaP film. As a result, the graphene–CaP nanocomposite demonstrated excellent mechanical durability, withstanding a 2 h sand abrasion test. It also exhibited excellent biocompatibility, as shown by the proliferation of human fibroblast cells for 7 days. The electrical properties remained stable under physiological conditions for 12 weeks, and the material maintained electrochemical stability after 1 million pulse cycles. Furthermore, it withstood the stress of 100,000 bending cycles without compromising electrical performance. This work highlights the versatility of the biocompatible graphene composite and its potential for a range of applications including free-form electronic circuits, electrodes, bending sensors, and electrothermal heaters
Текстовый файл
AM_Agreement
Sprog:engelsk
Udgivet: 2025
Fag:
Online adgang:https://doi.org/10.1021/acsami.4c21046
Format: Electronisk Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=681216

MARC

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330 |a Bone injuries remain a significant challenge, driving the development of new materials and technologies to enhance healing. This study presents a novel approach for incorporating graphene into calcium phosphate (CaP) coatings on titanium alloy (Ti) substrates, with the aim of creating a new generation of materials for bone implant electronics. The stability of the composite coating under physiological conditions, long-term electrical and mechanical durability, and biocompatibility were systematically investigated. We integrated graphene into the CaP coating through the laser processing of diazonium-functionalized graphene films applied to the surface of CaP-coated Ti. The laser treatment induced several processes, including the removal of aryl groups, the formation of conductive pathways, and chemical bonding with the CaP film. As a result, the graphene–CaP nanocomposite demonstrated excellent mechanical durability, withstanding a 2 h sand abrasion test. It also exhibited excellent biocompatibility, as shown by the proliferation of human fibroblast cells for 7 days. The electrical properties remained stable under physiological conditions for 12 weeks, and the material maintained electrochemical stability after 1 million pulse cycles. Furthermore, it withstood the stress of 100,000 bending cycles without compromising electrical performance. This work highlights the versatility of the biocompatible graphene composite and its potential for a range of applications including free-form electronic circuits, electrodes, bending sensors, and electrothermal heaters 
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461 1 |t ACS Applied Materials and Interfaces  |c Washington  |n American Chemical Society 
463 1 |t Vol. 17, iss. 9  |v P. 13527-13537  |d 2025 
610 1 |a graphene−calcium phosphate nanocomposites 
610 1 |a laser processing 
610 1 |a coatings 
610 1 |a bone implants 
610 1 |a biocompatible electronics 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
701 1 |a Dogadina  |b Е. М.  |c Specialist in the field of biotechnical technologies  |c Engineer of Tomsk Polytechnic University  |f 1998-  |g Elizaveta Maksimovna  |9 22848 
701 1 |a Rodriguez (Rodriges) Contreras  |b R. D.  |c Venezuelan physicist, doctor of science  |c Professor of Tomsk Polytechnic University  |f 1982-  |g Raul David  |9 21179 
701 1 |a Fatkullin  |b M. I.  |c chemical engineer  |c Engineer of Tomsk Polytechnic University  |f 1997-  |g Maksim Ilgizovich  |9 22844 
701 1 |a Lipovka  |b A. A.  |c chemist  |c Associate Scientist of Tomsk Polytechnic University  |f 1993-  |g Anna Anatolyevna  |9 21753 
701 1 |a Kozelskaya  |b A. I.  |c physicist  |c Researcher at Tomsk Polytechnic University, Candidate of Physical and Mathematical Sciences  |f 1985-  |g Anna Ivanovna  |9 21044 
701 1 |a Averkiev  |b A. A.  |c Specialist in the field of electronics  |c Research Engineer of Tomsk Polytechnic University  |f 1996-  |g Andrey Alekseevich  |9 22723 
701 1 |a Plotnikov  |b E. V.  |c chemist  |c Associate Professor of Tomsk Polytechnic University, Candidate of Chemical Sciences  |f 1983-  |g Evgeny Vladimirovich  |9 16417 
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701 1 |a Sheremet  |b E. S.  |c physicist  |c Professor of Tomsk Polytechnic University  |f 1988-  |g Evgeniya Sergeevna  |9 21197 
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