3D-printed biodegradable composite poly(lactic acid)-based scaffolds with a shape memory effect for bone tissue engineering; Advanced Composites and Hybrid Materials; Vol. 8, iss. 1
| Источник: | Advanced Composites and Hybrid Materials.— .— Basel: Springer Nature Switzerland AG Vol. 8, iss. 1.— 2025.— Article number 95, 20 p. |
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| Другие авторы: | , , , , , , , , , , , , |
| Примечания: | Title screen In this study, 3D-printed biodegradable poly(lactic acid) (PLA) and hybrid PLA scaffolds doped with magnetite nanoparticles (PLA/Fe3O4) and having gyroid structure were investigated at various infill densities (100%, 70%, 50%, or 30%). Effects of infill density on the composition, structure, and mechanical properties (Young’s modulus, compression, and tensile strength) of the scaffolds and a shape memory effect were documented. Raman spectroscopy was used to detect the characteristic molecular bonds of PLA and magnetite. X-ray diffraction confirmed higher crystallinity of the materials printed with Fe3O4 addition. PLA/Fe3O4 composites showed ferrimagnetic behavior. Mechanical properties of PLA/Fe3O4 composite scaffolds with 50% porosity fall within the range of corresponding mechanical properties of native cancellous bone, and therefore these scaffolds hold promise for the repair of bone defects. Additionally, 3D-printed materials’ various sizes and shapes were tested to achieve shape recovery up to 85% for composite porous scaffolds with gyroid structure and up to 100% for nonporous pure PLA ribbons (the supporting walls). Furthermore, a decrease in the infill density of the gyroid scaffolds resulted in a higher shape recovery rate. A proposed mechanism of the shape memory effect in the printed scaffolds was also discussed. These findings suggest that the developed 3D-printed PLA/Fe3O4 scaffolds, with tunable mechanical properties and shape memory capabilities, offer significant potential for advanced biomedical applications, including personalized bone repair and regeneration Текстовый файл AM_Agreement |
| Язык: | английский |
| Опубликовано: |
2025
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| Предметы: | |
| Online-ссылка: | https://doi.org/10.1007/s42114-024-01084-1 |
| Формат: | Электронный ресурс Статья |
| Запись в KOHA: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=680334 |
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| 200 | 1 | |a 3D-printed biodegradable composite poly(lactic acid)-based scaffolds with a shape memory effect for bone tissue engineering |f Abdullah bin Firoz, Vladimir Rybakov, Anastasia A. Fetisova [et al.] | |
| 203 | |a Текст |b визуальный |c электронный | ||
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| 330 | |a In this study, 3D-printed biodegradable poly(lactic acid) (PLA) and hybrid PLA scaffolds doped with magnetite nanoparticles (PLA/Fe3O4) and having gyroid structure were investigated at various infill densities (100%, 70%, 50%, or 30%). Effects of infill density on the composition, structure, and mechanical properties (Young’s modulus, compression, and tensile strength) of the scaffolds and a shape memory effect were documented. Raman spectroscopy was used to detect the characteristic molecular bonds of PLA and magnetite. X-ray diffraction confirmed higher crystallinity of the materials printed with Fe3O4 addition. PLA/Fe3O4 composites showed ferrimagnetic behavior. Mechanical properties of PLA/Fe3O4 composite scaffolds with 50% porosity fall within the range of corresponding mechanical properties of native cancellous bone, and therefore these scaffolds hold promise for the repair of bone defects. Additionally, 3D-printed materials’ various sizes and shapes were tested to achieve shape recovery up to 85% for composite porous scaffolds with gyroid structure and up to 100% for nonporous pure PLA ribbons (the supporting walls). Furthermore, a decrease in the infill density of the gyroid scaffolds resulted in a higher shape recovery rate. A proposed mechanism of the shape memory effect in the printed scaffolds was also discussed. These findings suggest that the developed 3D-printed PLA/Fe3O4 scaffolds, with tunable mechanical properties and shape memory capabilities, offer significant potential for advanced biomedical applications, including personalized bone repair and regeneration | ||
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| 461 | 1 | |t Advanced Composites and Hybrid Materials |c Basel |n Springer Nature Switzerland AG | |
| 463 | 1 | |t Vol. 8, iss. 1 |v Article number 95, 20 p. |d 2025 | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a Poly(lactic acid) | |
| 610 | 1 | |a Magnetite | |
| 610 | 1 | |a 3D printing | |
| 610 | 1 | |a Bone tissue engineering | |
| 610 | 1 | |a Shape memory effect | |
| 701 | 1 | |a Abdullah bin |b F. |g Firoz |f 1995- |c specialist in the field of material science |c Research Engineer of Tomsk Polytechnic University |9 88911 | |
| 701 | 1 | |a Rybakov |b V. A. |g Vladimir Andreevich |f 1994- |c specialist in the field of material science |c Engineer of Tomsk Polytechnic University |9 88905 | |
| 701 | 1 | |a Fetisova |b A. A. |g Anastasiya Alekseevna |f 2000- |c specialist in the field of material science |c Research Engineer of Tomsk Polytechnic University |9 88913 | |
| 701 | 1 | |a Shlapakova |b L. E. |c chemical engineer |c Research Engineer of Tomsk Polytechnic University |f 1999- |g Lada Evgenievna |9 88580 | |
| 701 | 1 | |a Pary (Pariy) |b I. O. |c physicist |c engineer of Tomsk Polytechnic University |f 1995- |g Igor Olegovich |9 21904 | |
| 701 | 1 | |a Toropkov |b N. |g Nikita | |
| 701 | 1 | |a Lozhkomoev |b A. S. |c specialist in the field of medical technology |c researcher of Tomsk Polytechnic University |f 1982- |g Aleksandr Sergeevich |9 18056 | |
| 701 | 1 | |a Mukhortova |b Yu. R. |c Chemical engineer |c Engineer of Tomsk Polytechnic University |f 1976- |g Yulia Ruslanovna |9 22264 | |
| 701 | 1 | |a Sharonova |b A. A. |c physicist |c laboratory assistant of Tomsk Polytechnic University |f 1990- |g Anna Aleksandrovna |9 18096 | |
| 701 | 1 | |a Vagner (Wagner) |b D. V. |c physicist |c Senior Researcher of Tomsk Polytechnic University, Candidate of technical sciences |f 1990- |g Dmitry Viktorovich |9 89321 | |
| 701 | 1 | |a Surmeneva |b M. A. |c specialist in the field of material science |c engineer-researcher of Tomsk Polytechnic University, Associate Scientist |f 1984- |g Maria Alexandrovna |9 15966 | |
| 701 | 1 | |a Kholkin |b A. L. |c physicist |c Director of the International Research Center for PMEM of the Tomsk Polytechnic University, Candidate of Physical and Mathematical Sciences |f 1954- |g Andrei Leonidovich |9 22787 | |
| 701 | 1 | |a Surmenev |b R. A. |c physicist |c Associate Professor of Tomsk Polytechnic University, Senior researcher, Candidate of physical and mathematical sciences |f 1982- |g Roman Anatolievich |9 15957 | |
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