Antibacterial Calcium Phosphate Coatings for Biomedical Applications Fabricated via Micro-Arc Oxidation; Biomimetics; Vol. 8, iss. 5
| Parent link: | Biomimetics.— .— Basel: MDPI AG Vol. 8, iss. 5.— 2023.— Article number 44, 16 p. |
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| Other Authors: | , , , , , , , , |
| Summary: | Title screen A promising method for improving the functional properties of calcium-phosphate coatings is the incorporation of various antibacterial additives into their structure. The microbial contamination of a superficial wound is inevitable, even if the rules of asepsis and antisepsis are optimally applied. One of the main problems is that bacteria often become resistant to antibiotics over time. However, this does not apply to certain elements, chemical compounds and drugs with antimicrobial properties. In this study, the fabrication and properties of zinc-containing calcium-phosphate coatings that were formed via micro-arc oxidation from three different electrolyte solutions are investigated. The first electrolyte is based on calcium oxide, the second on hydroxyapatite and the third on calcium acetate. By adding zinc oxide to the three electrolyte solutions, antibacterial properties of the coatings are achieved. Although the same amount of zinc oxide has been added to each electrolyte solution, the zinc concentration in the coatings obtained vary greatly. Furthermore, this study investigates the morphology, structure and chemical composition of the coatings. The antibacterial properties of the zinc-containing coatings were tested toward three strains of bacteria—Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. Coatings of calcium acetate and zinc oxide contained the highest amount of zinc and displayed the highest zinc release. Moreover, coatings containing hydroxyapatite and zinc oxide show the highest antibacterial activity toward Pseudomonas aeruginosa, and coatings containing calcium acetate and zinc oxide show the highest antibacterial activities toward Staphylococcus aureus and methicillin-resistant Staphylococcus aureus Текстовый файл |
| Language: | English |
| Published: |
2023
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| Subjects: | |
| Online Access: | https://doi.org/10.3390/biomimetics8050444 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=680069 |
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| 200 | 1 | |a Antibacterial Calcium Phosphate Coatings for Biomedical Applications Fabricated via Micro-Arc Oxidation |f Anna I. Kozelskaya, Ksenia N. Verzunova, Igor O. Akimchenko [et al.] | |
| 203 | |a Текст |b визуальный |c электронный | ||
| 283 | |a online_resource |2 RDAcarrier | ||
| 300 | |a Title screen | ||
| 320 | |a References: 66 tit | ||
| 330 | |a A promising method for improving the functional properties of calcium-phosphate coatings is the incorporation of various antibacterial additives into their structure. The microbial contamination of a superficial wound is inevitable, even if the rules of asepsis and antisepsis are optimally applied. One of the main problems is that bacteria often become resistant to antibiotics over time. However, this does not apply to certain elements, chemical compounds and drugs with antimicrobial properties. In this study, the fabrication and properties of zinc-containing calcium-phosphate coatings that were formed via micro-arc oxidation from three different electrolyte solutions are investigated. The first electrolyte is based on calcium oxide, the second on hydroxyapatite and the third on calcium acetate. By adding zinc oxide to the three electrolyte solutions, antibacterial properties of the coatings are achieved. Although the same amount of zinc oxide has been added to each electrolyte solution, the zinc concentration in the coatings obtained vary greatly. Furthermore, this study investigates the morphology, structure and chemical composition of the coatings. The antibacterial properties of the zinc-containing coatings were tested toward three strains of bacteria—Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. Coatings of calcium acetate and zinc oxide contained the highest amount of zinc and displayed the highest zinc release. Moreover, coatings containing hydroxyapatite and zinc oxide show the highest antibacterial activity toward Pseudomonas aeruginosa, and coatings containing calcium acetate and zinc oxide show the highest antibacterial activities toward Staphylococcus aureus and methicillin-resistant Staphylococcus aureus | ||
| 336 | |a Текстовый файл | ||
| 461 | 1 | |t Biomimetics |c Basel |n MDPI AG | |
| 463 | 1 | |t Vol. 8, iss. 5 |v Article number 44, 16 p. |d 2023 | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a bioactive coatings | |
| 610 | 1 | |a antibacterial coatings | |
| 610 | 1 | |a calcium phosphate coatings | |
| 610 | 1 | |a micro-arc oxidation | |
| 610 | 1 | |a zinc oxide | |
| 610 | 1 | |a biocompatibility | |
| 610 | 1 | |a antibacterial properties | |
| 610 | 1 | |a plasma electrolytic oxidation | |
| 610 | 1 | |a Gram-positive bacteria | |
| 610 | 1 | |a Gram-negative bacteria | |
| 701 | 1 | |a Kozelskaya |b A. I. |c physicist |c Researcher at Tomsk Polytechnic University, Candidate of Physical and Mathematical Sciences |f 1985- |g Anna Ivanovna |9 21044 | |
| 701 | 1 | |a Verzunova |b K. N. |g Kseniya Nikolaevna | |
| 701 | 1 | |a Akimchenko |b I. O. |c Physicist |c Engineer of Tomsk Polytechnic University |f 1996- |g Igor Olegovich |9 22643 | |
| 701 | 1 | |a Frueh |b J. Ch. |g Johannes Christoph | |
| 701 | 1 | |a Petrov |b V. I. |g Vsevolod Ivanovich | |
| 701 | 1 | |a Slepchenko |b G. B. |c Chemist |c Professor of Tomsk Polytechnic University, Doctor of chemical sciences |f 1956- |g Galina Borisovna |9 16858 | |
| 701 | 1 | |a Bakina |b O. V. |g Olga Vladimirovna | |
| 701 | 1 | |a Rutkowski |b S. |c chemist |c Research Engineer, Tomsk Polytechnic University, Ph.D |f 1981- |g Sven |9 22409 | |
| 701 | 1 | |a Tverdokhlebov |b S. I. |c physicist |c Associate Professor of Tomsk Polytechnic University, Candidate of physical and mathematical science |f 1961- |g Sergei Ivanovich |9 15101 | |
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