Methods of Analysis and Identification of Betulin and Its Derivatives; Molecules; Vol. 28, iss. 16

Methods of Analysis and Identification of Betulin and Its Derivatives; Molecules; Vol. 28, iss. 16

Detalhes bibliográficos
Parent link:Molecules.— .— Basel: MDPI AG
Vol. 28, iss. 16.— 2023.— Article number 5946, 23 p.
Outros Autores: Takibaeva A. T., Zhumabaeva G. K. Gulistan, Bakibaev A. A. Abdigali Abdimanapovich, Demets O. V. Olga, Lyapunova M. V. Mariya Viktorovna, Mamaeva E. A. Elena Andreevna, Yerkassov R. Sh. Rakhmetulla Sharapidenovich, Kassenov R. Zh., Ibraev M. K. Marat Kirimbaevich
Resumo:Title screen
This scientific work presents practical and theoretical material on the methods of analysis and identification of betulin and its key derivatives. The properties of betulin and its derivatives, which are determined by the structural features of this class of compounds and their tendency to form dimers, polymorphism and isomerization, are considered. This article outlines ways to improve not only the bioavailability but also the solubility of triterpenoids, as well as any hydrophobic drug substances, through chemical transformations by introducing various functional groups, such as carboxyl, hydroxyl, amino, phosphate/phosphonate and carbonyl. The authors of this article summarized the physicochemical characteristics of betulin and its compounds, systematized the literature data on IR and NMR spectroscopy and gave the melting temperatures of key acids and aldehydes based on betulin
Текстовый файл
Idioma:inglês
Publicado em: 2023
Assuntos:
электронный ресурс
труды учёных ТПУ
betulin
the solubility of pentacyclic triterpenoids
bioavailability
chemical transformation
Acesso em linha:https://doi.org/10.3390/molecules28165946
Formato: Recurso Electrónico Capítulo de Livro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=679761

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