6,8-Dibromo-11H-indeno[1,2-b]quinolin-11-one
| Parent link: | Molbank.— .— Basel: MDPI AG Vol. 2024, iss. 4.— 2024.— Article number M1922, 8 p. |
|---|---|
| Corporate Author: | National Research Tomsk Polytechnic University (570) |
| Other Authors: | Kovrizhina A. R. Anastasia Ruslanovna, Tolegen D. Dauren, Pavlov D. I. Dmitry Igorevich, Potapov A. S. Andrey Sergeevich, Khlebnikov A. I. Andrey Ivanovich |
| Summary: | Title screen We report the synthesis of the new compound 6,8-dibromo-11H-indeno[1,2-b]quinolin-11-one, which presents an important type of nitrogen-containing heterocycles and is a useful intermediate product in organic synthesis. The structure of the compound was confirmed by the single crystal X-ray diffraction. Molecular docking analysis revealed that 6,8-dibromo-11H-indeno[1,2-b]quinolin-11-one may effectively intercalate with DNA. The synthesized indenoquinoline derivative thus represents a promising lead compound for developing targeted anticancer and anti-inflammatory drugs Текстовый файл |
| Published: |
2024
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| Subjects: | |
| Online Access: | https://doi.org/10.3390/M1922 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=677973 |
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