6,8-Dibromo-11H-indeno[1,2-b]quinolin-11-one; Molbank; Vol. 2024, iss. 4

Détails bibliographiques
Parent link:	Molbank.— .— Basel: MDPI AG Vol. 2024, iss. 4.— 2024.— Article number M1922, 8 p.
Collectivité auteur:	National Research Tomsk Polytechnic University (570)
Autres auteurs:	Kovrizhina A. R. Anastasia Ruslanovna, Tolegen D. Dauren, Pavlov D. I. Dmitry Igorevich, Potapov A. S. Andrey Sergeevich, Khlebnikov A. I. Andrey Ivanovich
Résumé:	Title screen We report the synthesis of the new compound 6,8-dibromo-11H-indeno[1,2-b]quinolin-11-one, which presents an important type of nitrogen-containing heterocycles and is a useful intermediate product in organic synthesis. The structure of the compound was confirmed by the single crystal X-ray diffraction. Molecular docking analysis revealed that 6,8-dibromo-11H-indeno[1,2-b]quinolin-11-one may effectively intercalate with DNA. The synthesized indenoquinoline derivative thus represents a promising lead compound for developing targeted anticancer and anti-inflammatory drugs Текстовый файл
Langue:	anglais
Publié:	2024
Sujets:	indenoquinoline derivative crystal structure molecular docking электронный ресурс труды учёных ТПУ
Accès en ligne:	https://doi.org/10.3390/M1922
Format:	Électronique Chapitre de livre
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=677973

Internet

https://doi.org/10.3390/M1922