Bacterial inhibition and biofilm eradication ability of low-toxic deep eutectic solvents prepared from lactic acid and quaternary ammonium compounds; Materials Letters; Vol. 378
| Parent link: | Materials Letters.— .— Amsterdam: Elsevier Science Publishing Company Inc. Vol. 378.— 2025.— Article number 137591, 3 p. |
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| Diğer Yazarlar: | , , , , , , , , |
| Özet: | Title screen In the present communication, the preparation of deep eutectic solvents (DESs) based on an aqueous solution of lactic acid (LA) and two different quaternary ammonium compounds, choline chloride (ChCl) and tetraethylammonium chloride (TEAC), is proposed for the application as an antibacterial agent. The antibacterial and cytotoxic properties of the DESs obtained were studied and found to be highly effective in inhibiting both Gram-positive and Gram-negative bacteria and eradicating bacterial biofilms. Moreover, the DESs obtained exhibited reduced cytotoxicity towards soft tissue cells compared to the aqueous LA solution. The excellent antibacterial properties and low cytotoxicity of the DESs prepared make them a promising candidate for the development of novel antimicrobial agents or antibacterial eutectogels for delivery systems and tissue engineering applications Текстовый файл AM_Agreement |
| Dil: | İngilizce |
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2025
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| Online Erişim: | https://doi.org/10.1016/j.matlet.2024.137591 |
| Materyal Türü: | Elektronik Kitap Bölümü |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=677023 |