Bacterial inhibition and biofilm eradication ability of low-toxic deep eutectic solvents prepared from lactic acid and quaternary ammonium compounds; Materials Letters; Vol. 378

التفاصيل البيبلوغرافية
Parent link:Materials Letters.— .— Amsterdam: Elsevier Science Publishing Company Inc.
Vol. 378.— 2025.— Article number 137591, 3 p.
مؤلف مشترك: Томский политехнический университет (570)
مؤلفون آخرون: Dubinenko G. E. Gleb Evgenjevich, Myshova Aleksandra (Alexandra) Evgenjevna А. Е., Igumnova O. A. Olga Alekseevna, Golovina Kseniya Sergeevna K. S., Plotnikov E. V. Evgeny Vladimirovich, Badaraev A. D. Arsalan Dorzhievich, Rutkowski S. Sven, Filimonov V. D. Viktor Dmitrievich, Tverdokhlebov S. I. Sergei Ivanovich
الملخص:Title screen
In the present communication, the preparation of deep eutectic solvents (DESs) based on an aqueous solution of lactic acid (LA) and two different quaternary ammonium compounds, choline chloride (ChCl) and tetraethylammonium chloride (TEAC), is proposed for the application as an antibacterial agent. The antibacterial and cytotoxic properties of the DESs obtained were studied and found to be highly effective in inhibiting both Gram-positive and Gram-negative bacteria and eradicating bacterial biofilms. Moreover, the DESs obtained exhibited reduced cytotoxicity towards soft tissue cells compared to the aqueous LA solution. The excellent antibacterial properties and low cytotoxicity of the DESs prepared make them a promising candidate for the development of novel antimicrobial agents or antibacterial eutectogels for delivery systems and tissue engineering applications
Текстовый файл
AM_Agreement
اللغة:الإنجليزية
منشور في: 2025
الموضوعات:
الوصول للمادة أونلاين:https://doi.org/10.1016/j.matlet.2024.137591
التنسيق: الكتروني فصل الكتاب
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=677023

MARC

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200 1 |a Bacterial inhibition and biofilm eradication ability of low-toxic deep eutectic solvents prepared from lactic acid and quaternary ammonium compounds  |f Gleb E. Dubinenko, Alexandra E. Myshova, Olga A. Igumnova [et al.] 
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330 |a In the present communication, the preparation of deep eutectic solvents (DESs) based on an aqueous solution of lactic acid (LA) and two different quaternary ammonium compounds, choline chloride (ChCl) and tetraethylammonium chloride (TEAC), is proposed for the application as an antibacterial agent. The antibacterial and cytotoxic properties of the DESs obtained were studied and found to be highly effective in inhibiting both Gram-positive and Gram-negative bacteria and eradicating bacterial biofilms. Moreover, the DESs obtained exhibited reduced cytotoxicity towards soft tissue cells compared to the aqueous LA solution. The excellent antibacterial properties and low cytotoxicity of the DESs prepared make them a promising candidate for the development of novel antimicrobial agents or antibacterial eutectogels for delivery systems and tissue engineering applications 
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461 1 |t Materials Letters  |c Amsterdam  |n Elsevier Science Publishing Company Inc. 
463 1 |t Vol. 378  |v Article number 137591, 3 p.  |d 2025 
610 1 |a Deep eutectic solvents 
610 1 |a Lactic acid 
610 1 |a Quaternary ammonium compounds 
610 1 |a Choline chloride 
610 1 |a Tetraethylammonium chloride 
610 1 |a Antibacterial 
610 1 |a Biocompatible 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
701 1 |a Dubinenko  |b G. E.  |c Specialist in the field of material science  |c Engineer of Tomsk Polytechnic University  |f 1992-  |g Gleb Evgenjevich  |9 21551 
701 1 |a Myshova  |g Aleksandra (Alexandra) Evgenjevna  |b А. Е.  |f 2000-  |c specialist in the field of biotechnology  |c Engineer of Tomsk Polytechnic University  |9 88781 
701 1 |a Igumnova  |b O. A.  |g Olga Alekseevna 
701 1 |a Golovina  |g Kseniya Sergeevna  |b K. S.  |f 2000-  |c specialist in the field of biotechnology  |c Engineer of Tomsk Polytechnic University  |9 88783 
701 1 |a Plotnikov  |b E. V.  |c chemist  |c Associate Professor of Tomsk Polytechnic University, Candidate of Chemical Sciences  |f 1983-  |g Evgeny Vladimirovich  |9 16417 
701 1 |a Badaraev  |b A. D.  |c Physicist  |c Engineer of Tomsk Polytechnic University  |f 1995-  |g Arsalan Dorzhievich  |9 22441 
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701 1 |a Tverdokhlebov  |b S. I.  |c physicist  |c Associate Professor of Tomsk Polytechnic University, Candidate of physical and mathematical science  |f 1961-  |g Sergei Ivanovich  |9 15101 
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