Nanoparticles Partially Restore Bacterial Susceptibility to Antibiotics; Materials; Vol. 17, iss. 7

Nanoparticles Partially Restore Bacterial Susceptibility to Antibiotics; Materials; Vol. 17, iss. 7

Détails bibliographiques
Parent link:	Materials.— .— Basel: MDPI AG Vol. 17, iss. 7.— 2024.— Article number 1629, 13 p.
Collectivité auteur:	National Research Tomsk Polytechnic University (570)
Autres auteurs:	Bogdanchikova N. Nina, Vazquez-Gomez R. L. Roberto Luna, Nefedova E. V. Ekaterina Vladimirovna, Garibo D. Diana, Pestryakov A. N. Aleksey Nikolaevich, Plotnikov E. V. Evgeny Vladimirovich, Shkil N. N. Nikolay
Résumé:	Title screen The growing resistance of bacteria to antibiotics is one of the main public health problems nowadays. The influence of silver nanoparticle (AgNP) pretreatment of 220 cows with mastitis on the susceptibility of Staphylococcus epidermidis bacteria to 31 antibiotics was studied. The obtained results were compared with the previous results for Escherichia coli, Streptococcus dysgalactiae, and Staphylococcus aureus. For all four bacteria, an increase in susceptibility (9.5–21.2%) to 31 antibiotics after cow treatment with AgNPs was revealed, while after first-line antibiotic drug treatment as expected, the susceptibility decreased (11.3–27.3%). These effects were explained by (1) the increase in the contribution of isolates with efflux effect after antibiotic treatments and its decrease after AgNP treatment and (2) the changes in bacteria adhesion and anti-lysozyme activity after these treatments. The effect of the increasing antibacterial activity of antibiotics after AgNP treatment was the most pronounced in the case of E. coli and was minimal in the case of S. epidermidis. With AgNP treatment, the time of recovery decreased by 26.8–48.4% compared to the time of recovery after treatment with the first-line antibiotic drugs. The AgNP treatment allows for achieving the partial restoration of the activity of antibiotics. Текстовый файл
Langue:	anglais
Publié:	2024
Sujets:	электронный ресурс труды учёных ТПУ silver nanoparticles antibiotics drug-resistance partial recovery of susceptibility to antibiotics cow mastitis
Accès en ligne:	http://earchive.tpu.ru/handle/11683/132475 https://doi.org/10.3390/ma17071629
Format:	Électronique Chapitre de livre
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=673706

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