Biomimetic materials based on hydroxyapatite patterns for studying extracellular cell communication; Materials & Design; Vol. 238
| Parent link: | Materials & Design.— .— Amsterdam: Elsevier Science Publishing Company Inc. Vol. 238.— 2024.— Article number 112718, 11 p. |
|---|---|
| Autor Corporativo: | |
| Outros Autores: | , , , , , , , , , , |
| Resumo: | Title screen The study of cellular ion channels forms a basic understanding of healthy organ functioning and the body as a whole; however, the native role of signal transmission through ion channels between cells remains unclear. The success of the signal transmission investigation depends on the methods and materials used. Therefore, it is necessary to develop a new approach and system for studying detecting cell–cell communication. In this work, we suggest the system of hydroxyapatite patterns demonstrating piezoresponse in conjunction with fiber-based biosensors for detection of electrical signaling in cellular communities. Our system does not disrupt the integrity of cell membrane. The cells are located on self-assembled hydroxyapatite patterns forming the tissue patterns and communicating via spatially propagating waves of calcium, sodium, and potassium ions. These waves result from positive feedback caused by the activation of Ca2+ channels. The fiber-based ion-selective microelectrodes fixed above the patterns are used to detect the sodium, potassium, calcium ion currents in the extracellular space. We use norepinephrine to activate the Ca2+ channels result in intracellular Ca2+ release between the cell communities on different patterns. This system could be perspective as an efficient platform to lab-on-a-chip study as well as fundamental understanding of cellular communication during regeneration. Текстовый файл AM_Agreement |
| Idioma: | inglês |
| Publicado em: |
2024
|
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1016/j.matdes.2024.112718 |
| Formato: | Recurso Electrónico Capítulo de Livro |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=673489 |
MARC
| LEADER | 00000naa0a2200000 4500 | ||
|---|---|---|---|
| 001 | 673489 | ||
| 005 | 20240702151832.0 | ||
| 090 | |a 673489 | ||
| 100 | |a 20240702d2024 k||y0rusy50 ba | ||
| 101 | 0 | |a eng | |
| 102 | |a NL | ||
| 135 | |a drcn ---uucaa | ||
| 181 | 0 | |a i |b e | |
| 182 | 0 | |a b | |
| 183 | 0 | |a cr |2 RDAcarrier | |
| 200 | 1 | |a Biomimetic materials based on hydroxyapatite patterns for studying extracellular cell communication |f Polina I. Zyrianova, Mervat M. Eltantawy, Danil V. Silin [et al.] | |
| 203 | |a Текст |c электронный |b визуальный | ||
| 283 | |a online_resource |2 RDAcarrier | ||
| 300 | |a Title screen | ||
| 320 | |a References: 48 tit. | ||
| 330 | |a The study of cellular ion channels forms a basic understanding of healthy organ functioning and the body as a whole; however, the native role of signal transmission through ion channels between cells remains unclear. The success of the signal transmission investigation depends on the methods and materials used. Therefore, it is necessary to develop a new approach and system for studying detecting cell–cell communication. In this work, we suggest the system of hydroxyapatite patterns demonstrating piezoresponse in conjunction with fiber-based biosensors for detection of electrical signaling in cellular communities. Our system does not disrupt the integrity of cell membrane. The cells are located on self-assembled hydroxyapatite patterns forming the tissue patterns and communicating via spatially propagating waves of calcium, sodium, and potassium ions. These waves result from positive feedback caused by the activation of Ca2+ channels. The fiber-based ion-selective microelectrodes fixed above the patterns are used to detect the sodium, potassium, calcium ion currents in the extracellular space. We use norepinephrine to activate the Ca2+ channels result in intracellular Ca2+ release between the cell communities on different patterns. This system could be perspective as an efficient platform to lab-on-a-chip study as well as fundamental understanding of cellular communication during regeneration. | ||
| 336 | |a Текстовый файл | ||
| 371 | 0 | |a AM_Agreement | |
| 461 | 1 | |t Materials & Design |c Amsterdam |n Elsevier Science Publishing Company Inc. | |
| 463 | 1 | |t Vol. 238 |v Article number 112718, 11 p. |d 2024 | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a Calcium signaling | |
| 610 | 1 | |a Cell communication | |
| 610 | 1 | |a Liesegang rings | |
| 610 | 1 | |a Ion-selective electrode | |
| 610 | 1 | |a Layer-by-layer assembly | |
| 610 | 1 | |a C2C12 cell line | |
| 701 | 1 | |a Zyrianova |b P. I. |g Polina | |
| 701 | 1 | |a Eltantawy |b M. M. |g Mervat | |
| 701 | 1 | |a Silin |b D. V. |g Danil | |
| 701 | 1 | |a Korolev |b I. S. |g Ilya | |
| 701 | 1 | |a Nikolaev |b K. G. |g Konstantin | |
| 701 | 1 | |a Kozodaev |b D. A. |g Dmitry | |
| 701 | 1 | |a Slautina |b A, S. |g Alla | |
| 701 | 1 | |a Surmenev |b R. A. |c physicist |c Associate Professor of Tomsk Polytechnic University, Senior researcher, Candidate of physical and mathematical sciences |f 1982- |g Roman Anatolievich |9 15957 | |
| 701 | 1 | |a Kholkin |b A. L. |c physicist |c Director of the International Research Center for PMEM of the Tomsk Polytechnic University, Candidate of Physical and Mathematical Sciences |f 1954- |g Andrei Leonidovich |9 22787 | |
| 701 | 1 | |a Ulasevich |b S. A. |g Sviatlana | |
| 701 | 1 | |a Skorb |b E. V. |g Ekaterina | |
| 712 | 0 | 2 | |a National Research Tomsk Polytechnic University |9 27197 |4 570 |
| 801 | 0 | |a RU |b 63413507 |c 20240702 |g RCR | |
| 856 | 4 | |u https://doi.org/10.1016/j.matdes.2024.112718 |z https://doi.org/10.1016/j.matdes.2024.112718 | |
| 942 | |c CR | ||