Synthesis and Properties of a Water-Soluble Ureide Derived from Gаlodif and Succinic Acid; Russian Journal of Organic Chemistry; Vol. 59, No. 9

Bibliographic Details
Parent link:Russian Journal of Organic Chemistry.— .— New York: Springer Science+Business Media LLC.
Vol. 59, No. 9.— 2023.— P. 1629–1632
Other Authors: Kuksenok V. Yu. Vera Yurievna, Cui Yanwen, Shtrykova V. V. Viktoriya Viktorovna, Filimonov V. D. Viktor Dmitrievich, Shushpanova T. V. Tamara Vladimirovna
Summary:Title screen
A new ureide has been synthesized by acylation of the anticonvulsant and anti-alcohol drug galodif N-[(3-chlorophenyl)(phenyl)methyl]urea with succinic anhydride in the presence of some acids. Unlike galodif which is almost insoluble in water, the synthesized ureide is soluble in aqueous media. It is expected to exhibit higher bioavailability and is promising as a liquid drug dosage form and a prodrug with prolonged action
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Language:English
Published: 2023
Subjects:
Online Access:https://doi.org/10.1134/S1070428023090221
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=672391

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