Synthesis and Properties of a Water-Soluble Ureide Derived from Gаlodif and Succinic Acid; Russian Journal of Organic Chemistry; Vol. 59, No. 9
| Parent link: | Russian Journal of Organic Chemistry.— .— New York: Springer Science+Business Media LLC. Vol. 59, No. 9.— 2023.— P. 1629–1632 |
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| Tác giả khác: | , , , , |
| Tóm tắt: | Title screen A new ureide has been synthesized by acylation of the anticonvulsant and anti-alcohol drug galodif N-[(3-chlorophenyl)(phenyl)methyl]urea with succinic anhydride in the presence of some acids. Unlike galodif which is almost insoluble in water, the synthesized ureide is soluble in aqueous media. It is expected to exhibit higher bioavailability and is promising as a liquid drug dosage form and a prodrug with prolonged action Текстовый файл AM_Agreement |
| Ngôn ngữ: | Tiếng Anh |
| Được phát hành: |
2023
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| Những chủ đề: | |
| Truy cập trực tuyến: | https://doi.org/10.1134/S1070428023090221 |
| Định dạng: | Điện tử Chương của sách |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=672391 |
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| 200 | 1 | |a Synthesis and Properties of a Water-Soluble Ureide Derived from Gаlodif and Succinic Acid |f V. Yu. Kuksenok, Y. Cui, V. V. Shtrykova [et al.] | |
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| 300 | |a Title screen | ||
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| 330 | |a A new ureide has been synthesized by acylation of the anticonvulsant and anti-alcohol drug galodif N-[(3-chlorophenyl)(phenyl)methyl]urea with succinic anhydride in the presence of some acids. Unlike galodif which is almost insoluble in water, the synthesized ureide is soluble in aqueous media. It is expected to exhibit higher bioavailability and is promising as a liquid drug dosage form and a prodrug with prolonged action | ||
| 336 | |a Текстовый файл | ||
| 371 | 0 | |a AM_Agreement | |
| 461 | 1 | |t Russian Journal of Organic Chemistry |c New York |n Springer Science+Business Media LLC. | |
| 463 | 1 | |t Vol. 59, No. 9 |v P. 1629–1632 |d 2023 | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a acylation of ureas | |
| 610 | 1 | |a galodif | |
| 610 | 1 | |a benzhydrylureas | |
| 610 | 1 | |a ureides | |
| 610 | 1 | |a succinic acid | |
| 610 | 1 | |a anticonvulsants | |
| 701 | 1 | |a Kuksenok |b V. Yu. |c chemist |c Senior Lecturer of Tomsk Polytechnic University, Candidate of Chemical Sciences |f 1989- |g Vera Yurievna |9 16412 | |
| 701 | 0 | |a Cui Yanwen | |
| 701 | 1 | |a Shtrykova |b V. V. |c chemist |c Associate professor of Tomsk Polytechnic University, Candidate of chemical sciences |f 1962- |g Viktoriya Viktorovna |9 15959 | |
| 701 | 1 | |a Filimonov |b V. D. |c Russian chemist |c Professor of the TPU |f 1945- |g Viktor Dmitrievich |9 12127 | |
| 701 | 1 | |a Shushpanova |b T. V. |g Tamara Vladimirovna | |
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| 856 | 4 | |u https://doi.org/10.1134/S1070428023090221 |z https://doi.org/10.1134/S1070428023090221 | |
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