Synthesis and Properties of a Water-Soluble Ureide Derived from Gаlodif and Succinic Acid; Russian Journal of Organic Chemistry; Vol. 59, No. 9
| Parent link: | Russian Journal of Organic Chemistry.— .— New York: Springer Science+Business Media LLC. Vol. 59, No. 9.— 2023.— P. 1629–1632 |
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| 其他作者: | , , , , |
| 總結: | Title screen A new ureide has been synthesized by acylation of the anticonvulsant and anti-alcohol drug galodif N-[(3-chlorophenyl)(phenyl)methyl]urea with succinic anhydride in the presence of some acids. Unlike galodif which is almost insoluble in water, the synthesized ureide is soluble in aqueous media. It is expected to exhibit higher bioavailability and is promising as a liquid drug dosage form and a prodrug with prolonged action Текстовый файл AM_Agreement |
| 語言: | 英语 |
| 出版: |
2023
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| 主題: | |
| 在線閱讀: | https://doi.org/10.1134/S1070428023090221 |
| 格式: | 電子 Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=672391 |
| 總結: | Title screen A new ureide has been synthesized by acylation of the anticonvulsant and anti-alcohol drug galodif N-[(3-chlorophenyl)(phenyl)methyl]urea with succinic anhydride in the presence of some acids. Unlike galodif which is almost insoluble in water, the synthesized ureide is soluble in aqueous media. It is expected to exhibit higher bioavailability and is promising as a liquid drug dosage form and a prodrug with prolonged action Текстовый файл AM_Agreement |
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| DOI: | 10.1134/S1070428023090221 |