Electrochemical Sensor for Selective Detection of Meldonium in Urine by Voltammetry; Electroanalysis; Vol. 34

Detaylı Bibliyografya
Parent link:Electroanalysis
Vol. 34.— 2022.— [P. 1–9]
Müşterek Yazar: Национальный исследовательский Томский политехнический университет Инженерная школа природных ресурсов Отделение химической инженерии
Diğer Yazarlar: Mezentseva O. L. Olga Leonidovna, Slepchenko G. B. Galina Borisovna, Dorozhko E. V. Elena Vladimirovna, Moiseeva E. S. Evgeniya Sergeevna, Kryukovsky V. P. Vladimir Petrovich, Zaytsev N. K. Nikolay Konkordjevich
Özet:Title screen
A highly sensitive electrochemical sensor based on arenediazonium tosylates was designed to detect meldonium in urine. The effect of the concentration of ArN2+OTs? arenediazonium tosylate modifier and various substituents was studied. Basic operating parameters for voltammetric meldonium detection were established and the procedure for urine sample preparation was developed. The following values were obtained: limit of detection (LOD) 0.005 mg ? L?1 (P=0.95) and limit of quantification (LOQ) 0.01 mg ? L?1. The relationship between the analytical signal and meldonium concentration in the solution ranging from 0.01 to 400 mg ? L?1 was described by a linear function. The meldonium concentration error did not exceed 18 %. The analysis time for a single urine sample was reduced to 15 minutes.
Режим доступа: по договору с организацией-держателем ресурса
Dil:İngilizce
Baskı/Yayın Bilgisi: 2022
Konular:
Online Erişim:https://doi.org/10.1002/elan.202200252
Materyal Türü: MixedMaterials Elektronik Kitap Bölümü
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668940

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200 1 |a Electrochemical Sensor for Selective Detection of Meldonium in Urine by Voltammetry  |f O. L. Mezentseva, G. B. Slepchenko, E. V. Dorozhko [et al.] 
203 |a Text  |c electronic 
300 |a Title screen 
320 |a [References: 22 tit.] 
330 |a A highly sensitive electrochemical sensor based on arenediazonium tosylates was designed to detect meldonium in urine. The effect of the concentration of ArN2+OTs? arenediazonium tosylate modifier and various substituents was studied. Basic operating parameters for voltammetric meldonium detection were established and the procedure for urine sample preparation was developed. The following values were obtained: limit of detection (LOD) 0.005 mg ? L?1 (P=0.95) and limit of quantification (LOQ) 0.01 mg ? L?1. The relationship between the analytical signal and meldonium concentration in the solution ranging from 0.01 to 400 mg ? L?1 was described by a linear function. The meldonium concentration error did not exceed 18 %. The analysis time for a single urine sample was reduced to 15 minutes. 
333 |a Режим доступа: по договору с организацией-держателем ресурса 
461 |t Electroanalysis 
463 |t Vol. 34  |v [P. 1–9]  |d 2022 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
610 1 |a sensor 
610 1 |a arenediazonium tosylates 
610 1 |a meldonium 
610 1 |a voltammetry 
610 1 |a urine 
701 1 |a Mezentseva  |b O. L.  |g Olga Leonidovna 
701 1 |a Slepchenko  |b G. B.  |c Chemist  |c Professor of Tomsk Polytechnic University, Doctor of chemical sciences  |f 1956-  |g Galina Borisovna  |3 (RuTPU)RU\TPU\pers\33018  |9 16858 
701 1 |a Dorozhko  |b E. V.  |c chemist  |c Engineer of Tomsk Polytechnic University  |f 1979-  |g Elena Vladimirovna  |3 (RuTPU)RU\TPU\pers\32174  |9 16175 
701 1 |a Moiseeva  |b E. S.  |c chemical engineer  |c Metrology Engineer of the second category of Tomsk Polytechnic University, Candidate of chemical sciences  |f 1980-  |g Evgeniya Sergeevna  |3 (RuTPU)RU\TPU\pers\45381 
701 1 |a Kryukovsky  |b V. P.  |g Vladimir Petrovich 
701 1 |a Zaytsev  |b N. K.  |g Nikolay Konkordjevich 
712 0 2 |a Национальный исследовательский Томский политехнический университет  |b Инженерная школа природных ресурсов  |b Отделение химической инженерии  |3 (RuTPU)RU\TPU\col\23513 
801 0 |a RU  |b 63413507  |c 20230203  |g RCR 
856 4 |u https://doi.org/10.1002/elan.202200252 
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