Chronic toxicity of shrimp feed added with silver nanoparticles (Argovit-4®) in Litopenaeus vannamei and immune response to white spot syndrome virus infection; PeerJ; Vol. 10

Bibliographic Details
Parent link:PeerJ
Vol. 10.— 2022.— [e14231, 22 p.]
Corporate Author: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Other Authors: Romo-Quinonez C. R. Carlos, Alvarez-Ruiz P. Pindaro, Mejia-Ruiz C. H., Bogdanchikova N. Nina, Pestryakov A. N. Aleksey Nikolaevich, Gamez-Jimenez C. Carina, Valenzuela-Quinonez W. Wenceslao, Montoya-Mejia M. Magnolia, Perez E. N. Eusebio Nava
Summary:Title screen
In recent years, the application of silver nanoparticles (AgNPs) as antibacterial compounds has been widely used in human and veterinary medicine. In this work, we investigated the effects of AgNPs (Argovit-4®) as feed additives (feed-AgNPs) on shrimp (Litopenaeus vannamei) using three different methods: 1) chronic toxicity after 28 days of feeding, 2) Effects against white spot syndrome virus (WSSV) challenged by oral route, and 3) transcriptional responses of immune-related genes (PAP, ProPO, CTL-3, Crustin, PEN3, and PEN4) following WSSV infection. The results showed that the feed-AgNPs did not interfere with the growth and survival of shrimp. Also, mild lesions in the hepatopancreas were recorded, proportional to the frequency of the feed-AgNP supply. Challenge test versus WSSV showed that feeding every 7 days with feed-AgNPs reduced mortality, reaching a survival rate of 53%, compared to the survival rates observed in groups fed every 4 days, daily and control groups of feed-AgNPs for the 30%, 10%, and 7% groups, respectively. Feed-AgNPs negatively regulated the expression of PAP, ProPO, and Crustin genes after 28 days of treatment and altered the transcriptional responses of PAP, ProPO, CTL-3, and Crustin after WSSV exposure. The results showed that weekly feeding-AgNPs could partially prevent WSSV infection in shrimp culture. However, whether or not transcriptional responses against pathogens are advantageous remains to be elucidated.
Language:English
Published: 2022
Subjects:
Online Access:https://doi.org/10.7717/peerj.14231
Format: MixedMaterials Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668884

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200 1 |a Chronic toxicity of shrimp feed added with silver nanoparticles (Argovit-4®) in Litopenaeus vannamei and immune response to white spot syndrome virus infection  |f C. R. Romo-Quinonez, P. Alvarez-Ruiz, C. H. Mejia-Ruiz [et al.] 
203 |a Text  |c electronic 
300 |a Title screen 
330 |a In recent years, the application of silver nanoparticles (AgNPs) as antibacterial compounds has been widely used in human and veterinary medicine. In this work, we investigated the effects of AgNPs (Argovit-4®) as feed additives (feed-AgNPs) on shrimp (Litopenaeus vannamei) using three different methods: 1) chronic toxicity after 28 days of feeding, 2) Effects against white spot syndrome virus (WSSV) challenged by oral route, and 3) transcriptional responses of immune-related genes (PAP, ProPO, CTL-3, Crustin, PEN3, and PEN4) following WSSV infection. The results showed that the feed-AgNPs did not interfere with the growth and survival of shrimp. Also, mild lesions in the hepatopancreas were recorded, proportional to the frequency of the feed-AgNP supply. Challenge test versus WSSV showed that feeding every 7 days with feed-AgNPs reduced mortality, reaching a survival rate of 53%, compared to the survival rates observed in groups fed every 4 days, daily and control groups of feed-AgNPs for the 30%, 10%, and 7% groups, respectively. Feed-AgNPs negatively regulated the expression of PAP, ProPO, and Crustin genes after 28 days of treatment and altered the transcriptional responses of PAP, ProPO, CTL-3, and Crustin after WSSV exposure. The results showed that weekly feeding-AgNPs could partially prevent WSSV infection in shrimp culture. However, whether or not transcriptional responses against pathogens are advantageous remains to be elucidated. 
461 |t PeerJ 
463 |t Vol. 10  |v [e14231, 22 p.]  |d 2022 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
610 1 |a silver nanoparticles 
610 1 |a shrimp 
610 1 |a aquaculture 
610 1 |a chronic toxicity 
610 1 |a WSSV 
610 1 |a AgNP 
610 1 |a argovit 
610 1 |a litopenaeus vannamei 
610 1 |a silver fed 
610 1 |a white spot syndrome virus 
610 1 |a наночастицы 
610 1 |a интоксикации 
701 1 |a Romo-Quinonez  |b C. R.  |g Carlos 
701 1 |a Alvarez-Ruiz  |b P.  |g Pindaro 
701 1 |a Mejia-Ruiz  |b C. H. 
701 1 |a Bogdanchikova  |b N.  |g Nina 
701 1 |a Pestryakov  |b A. N.  |c Chemist  |c Professor of Tomsk Polytechnic University, Doctor of Chemical Science  |f 1963-  |g Aleksey Nikolaevich  |3 (RuTPU)RU\TPU\pers\30471  |9 14796 
701 1 |a Gamez-Jimenez  |b C.  |g Carina 
701 1 |a Valenzuela-Quinonez  |b W.  |g Wenceslao 
701 1 |a Montoya-Mejia  |b M.  |g Magnolia 
701 1 |a Perez  |b E. N.  |g Eusebio Nava 
712 0 2 |a Национальный исследовательский Томский политехнический университет  |b Исследовательская школа химических и биомедицинских технологий  |c (2017- )  |3 (RuTPU)RU\TPU\col\23537 
801 0 |a RU  |b 63413507  |c 20230131  |g RCR 
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