Efficient Catalytic Synthesis of Condensed Isoxazole Derivatives via Intramolecular Oxidative Cycloaddition of Aldoximes; Molecules; Vol. 27, iss. 12

Xehetasun bibliografikoak
Parent link:Molecules
Vol. 27, iss. 12.— 2022.— [3860, 13 p.]
Erakunde egilea: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Beste egile batzuk: Mironova I. A. Irina Andreevna, Nenaydenko V. G. Valentin Georgievich, Postnikov P. S. Pavel Sergeevich, Saito Akio, Yusubov M. S. Mekhman Suleiman-Ogly (Suleimanovich), Yoshimura A. Akira
Gaia:Title screen
The intramolecular oxidative cycloaddition reaction of alkyne- or alkene-tethered aldoximes was catalyzed efficiently by hypervalent iodine(III) species to afford the corresponding polycyclic isoxazole derivatives in up to a 94% yield. The structure of the prepared products was confirmed by various methods, including X-ray crystallography. Mechanistic study demonstrated the crucial role of hydroxy(aryl)iodonium tosylate as a precatalyst, which is generated from 2-iodobenzoic acid and m-chloroperoxybenzoic acid in the presence of a catalytic amount of p-toluenesulfonic acid.
Hizkuntza:ingelesa
Argitaratua: 2022
Gaiak:
Sarrera elektronikoa:https://doi.org/10.3390/molecules27123749
Formatua: MixedMaterials Baliabide elektronikoa Liburu kapitulua
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668602

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200 1 |a Efficient Catalytic Synthesis of Condensed Isoxazole Derivatives via Intramolecular Oxidative Cycloaddition of Aldoximes  |f I. A. Mironova, V. G. Nenaydenko, P. S. Postnikov [et al.] 
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330 |a The intramolecular oxidative cycloaddition reaction of alkyne- or alkene-tethered aldoximes was catalyzed efficiently by hypervalent iodine(III) species to afford the corresponding polycyclic isoxazole derivatives in up to a 94% yield. The structure of the prepared products was confirmed by various methods, including X-ray crystallography. Mechanistic study demonstrated the crucial role of hydroxy(aryl)iodonium tosylate as a precatalyst, which is generated from 2-iodobenzoic acid and m-chloroperoxybenzoic acid in the presence of a catalytic amount of p-toluenesulfonic acid. 
461 |t Molecules 
463 |t Vol. 27, iss. 12  |v [3860, 13 p.]  |d 2022 
610 1 |a труды учёных ТПУ 
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