Gram-scale synthesis of carboxylic acids via catalytic acceptorless dehydrogenative coupling of alcohols and hydroxides at an ultralow Ru loading

Bibliographic Details
Parent link:Applied Catalysis A: General
Vol. 630.— 2022.— [118443, 12 p.]
Corporate Author: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Other Authors: Wu Zhe, Zhi-Qin Wang, Cheng Hua, Zheng Zhong-Hui, Yuan Ye, Chen Cheng E. Elkadi, Verpoort F. V. K. Frensis Valter Kornelius
Summary:Title screen
Acceptorless dehydrogenative coupling (ADC) of alcohols and water/hydroxides is an emergent and graceful approach to produce carboxylic acids. Therefore, it is of high demand to develop active and practical catalysts/catalytic systems for this attractive transformation. Herein, we designed and fabricated a series of cyclometallated N-heterocyclic carbene-Ru (NHC-Ru) complexes via ligand tuning of [Ru-1], the superior complex in our previous work. Gratifyingly, gram-scale synthesis of carboxylic acids was efficiently enabled at an ultralow Ru loading (62.5 ppm) in open air. Moreover, effects of distinct ancillary NHC ligands and other parameters on this catalytic process were thoroughly studied, while further systematic studies were carried out to provide rationales for the activity trend of [Ru-1]-[Ru-7]. Finally, determination of quantitative green metrics illustrated that the present work exhibited superiority over representative literature reports. Hopefully, this study could provide valuable input for researchers who are engaging in metal-catalyzed ADC reactions.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2022
Subjects:
Online Access:https://doi.org/10.1016/j.apcata.2021.118443
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668559

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200 1 |a Gram-scale synthesis of carboxylic acids via catalytic acceptorless dehydrogenative coupling of alcohols and hydroxides at an ultralow Ru loading  |f Wu Zhe, Zhi-Qin Wang, Cheng Hua [et al.] 
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300 |a Title screen 
320 |a [References: 62 tit.] 
330 |a Acceptorless dehydrogenative coupling (ADC) of alcohols and water/hydroxides is an emergent and graceful approach to produce carboxylic acids. Therefore, it is of high demand to develop active and practical catalysts/catalytic systems for this attractive transformation. Herein, we designed and fabricated a series of cyclometallated N-heterocyclic carbene-Ru (NHC-Ru) complexes via ligand tuning of [Ru-1], the superior complex in our previous work. Gratifyingly, gram-scale synthesis of carboxylic acids was efficiently enabled at an ultralow Ru loading (62.5 ppm) in open air. Moreover, effects of distinct ancillary NHC ligands and other parameters on this catalytic process were thoroughly studied, while further systematic studies were carried out to provide rationales for the activity trend of [Ru-1]-[Ru-7]. Finally, determination of quantitative green metrics illustrated that the present work exhibited superiority over representative literature reports. Hopefully, this study could provide valuable input for researchers who are engaging in metal-catalyzed ADC reactions. 
333 |a Режим доступа: по договору с организацией-держателем ресурса 
461 |t Applied Catalysis A: General 
463 |t Vol. 630  |v [118443, 12 p.]  |d 2022 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
610 1 |a gram-scale synthesis 
610 1 |a carboxylic acids 
610 1 |a Acceptorless dehydrogenative coupling (ADC) 
610 1 |a N-heterocyclic carbene-Ru (NHC-Ru) 
610 1 |a ultralow loading 
610 1 |a синтез 
610 1 |a карбоновые кислоты 
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701 0 |a Zheng Zhong-Hui 
701 0 |a Yuan Ye 
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