Pulsed Vacuum Arc Deposition of Nitrogen-Doped Diamond-like Coatings for Long-Term Hydrophilicity of Electrospun Poly(ε-caprolactone) Scaffolds; Membranes; Vol. 12, iss. 11

Pulsed Vacuum Arc Deposition of Nitrogen-Doped Diamond-like Coatings for Long-Term Hydrophilicity of Electrospun Poly(ε-caprolactone) Scaffolds; Membranes; Vol. 12, iss. 11

Detalhes bibliográficos
Parent link:Membranes
Vol. 12, iss. 11.— 2022.— [1080, 9 p.]
Corporate Authors: Национальный исследовательский Томский политехнический университет Инженерная школа новых производственных технологий Научно-образовательный центр Н. М. Кижнера, Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Научно-образовательный центр Б. П. Вейнберга
Outros Autores: Goreninsky (Goreninskii) S. I. Semen Igorevich, Yuriev Yu. N. Yuri Nikolaevich, Runts A. A. Artem Alekseevich, Prosetskaya E. A. Elizaveta Alekseevna, Sviridova E. V. Elizaveta Vitaljevna, Plotnikov E. V. Evgeny Vladimirovich, Stankevich K. S. Ksenia Sergeevna, Bolbasov E. N. Evgeny Nikolaevich
Resumo:Title screen
The surface hydrophobicity of poly(ε-caprolactone) electrospun scaffolds prevents their interactions with cells and tissue integration. Although plasma treatment of scaffolds enhances their hydrophilicity, this effect is temporary, and the hydrophobicity of the scaffolds is restored in about 30 days. In this communication, we report a method for hydrophilization of poly(ε-caprolactone) electrospun scaffolds for more than 6 months. To that end, diamond-like coating was deposited on the surface of the scaffolds in a nitrogen atmosphere using pulsed vacuum arc deposition with sputtering of graphite target. This approach allows for a single-side hydrophilization of the scaffold (water contact angle of 22 ± 3° vs. 126 ± 2° for pristine PCL scaffold) and preserves its structure. With increased nitrogen pressure in the chamber, sp3-hybridized carbon content decreased twice (sp2/sp3 ratio decreased from 1.06 to 0.52), which demonstrates the possibility of tailoring the content of carbon in sp2 and sp3 hybridization state. Nitrogen content in the deposited coatings was found at 16.1 ± 0.9 at.%. In vitro tests with fibroblast cell culture did not reveal any cytotoxic compounds in sample extracts.
Idioma:inglês
Publicado em: 2022
Assuntos:
электронный ресурс
труды учёных ТПУ
diamond-like coatings
electrospun scaffolds
polycaprolactone
biomaterials
алмазоподобные покрытия
поликапролактон
биоматериалы
Acesso em linha:http://earchive.tpu.ru/handle/11683/74885
https://doi.org/10.3390/membranes12111080
Formato: Recurso Electrónico Capítulo de Livro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668434

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