Surface Modification of Electrospun Bioresorbable and Biostable Scaffolds by Pulsed DC Magnetron Sputtering of Titanium for Gingival Tissue Regeneration; Polymers; Vol. 14, iss. 22
| Parent link: | Polymers Vol. 14, iss. 22.— 2022.— [4922, 19 p. ] |
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| Ente Autore: | |
| Altri autori: | , , , , , , , , |
| Riassunto: | In this study, polymer scaffolds were fabricated from biodegradable poly(lactide-co-glycolide) (PLGA) and from non-biodegradable vinylidene fluoride-tetrafluoroethylene (VDF-TeFE) by electrospinning. These polymer scaffolds were subsequently surface-modified by sputtering titanium targets in an argon atmosphere. Direct current pulsed magnetron sputtering was applied to prevent a significant influence of discharge plasma on the morphology and mechanical properties of the nonwoven polymer scaffolds. The scaffolds with initially hydrophobic properties show higher hydrophilicity and absorbing properties after surface modification with titanium. The surface modification by titanium significantly increases the cell adhesion of both the biodegradable and the non-biodegradable scaffolds. Immunocytochemistry investigations of human gingival fibroblast cells on the surface-modified scaffolds indicate that a PLGA scaffold exhibits higher cell adhesion than a VDF-TeFE scaffold. |
| Lingua: | inglese |
| Pubblicazione: |
2022
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| Soggetti: | |
| Accesso online: | http://earchive.tpu.ru/handle/11683/74803 https://doi.org/10.3390/polym14224922 |
| Natura: | Elettronico Capitolo di libro |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668416 |
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| 200 | 1 | |a Surface Modification of Electrospun Bioresorbable and Biostable Scaffolds by Pulsed DC Magnetron Sputtering of Titanium for Gingival Tissue Regeneration |f A. D. Badaraev, D. V. Sidelev, A. I. Kozelskaya [et al.] | |
| 203 | |a Text |c electronic | ||
| 320 | |a [References: 71 tit.] | ||
| 330 | |a In this study, polymer scaffolds were fabricated from biodegradable poly(lactide-co-glycolide) (PLGA) and from non-biodegradable vinylidene fluoride-tetrafluoroethylene (VDF-TeFE) by electrospinning. These polymer scaffolds were subsequently surface-modified by sputtering titanium targets in an argon atmosphere. Direct current pulsed magnetron sputtering was applied to prevent a significant influence of discharge plasma on the morphology and mechanical properties of the nonwoven polymer scaffolds. The scaffolds with initially hydrophobic properties show higher hydrophilicity and absorbing properties after surface modification with titanium. The surface modification by titanium significantly increases the cell adhesion of both the biodegradable and the non-biodegradable scaffolds. Immunocytochemistry investigations of human gingival fibroblast cells on the surface-modified scaffolds indicate that a PLGA scaffold exhibits higher cell adhesion than a VDF-TeFE scaffold. | ||
| 461 | |t Polymers | ||
| 463 | |t Vol. 14, iss. 22 |v [4922, 19 p. ] |d 2022 | ||
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a electrospinning | |
| 610 | 1 | |a pulsed DC magnetron sputtering | |
| 610 | 1 | |a titanium coating | |
| 610 | 1 | |a plasma surface modification | |
| 610 | 1 | |a polymer scaffolds | |
| 610 | 1 | |a gingival fibroblasts | |
| 610 | 1 | |a PLGA | |
| 610 | 1 | |a VDF-TeFE | |
| 610 | 1 | |a электропрядение | |
| 610 | 1 | |a импульсное магнетронное распыление | |
| 610 | 1 | |a постоянный ток | |
| 610 | 1 | |a титановые покрытия | |
| 610 | 1 | |a модификации | |
| 610 | 1 | |a полимерные каркасы | |
| 701 | 1 | |a Badaraev |b A. D. |c Physicist |c Engineer of Tomsk Polytechnic University |f 1995- |g Arsalan Dorzhievich |3 (RuTPU)RU\TPU\pers\46819 |9 22441 | |
| 701 | 1 | |a Sidelev |b D. V. |c physicist |c Associate Professor of Tomsk Polytechnic University, Candidate of Technical Sciences |f 1991- |g Dmitry Vladimirovich |y Tomsk |3 (RuTPU)RU\TPU\pers\34524 |9 17905 | |
| 701 | 1 | |a Kozelskaya |b A. I. |c physicist |c Researcher at Tomsk Polytechnic University, Candidate of Physical and Mathematical Sciences |f 1985- |g Anna Ivanovna |3 (RuTPU)RU\TPU\pers\39663 |9 21044 | |
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| 701 | 0 | |a Tran Tuan Hoang |c specialist in the field of nuclear technologies |c engineer of Tomsk Polytechnic University |f 1993- |3 (RuTPU)RU\TPU\pers\47572 | |
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