Core-Shell Magnetoactive PHB/Gelatin/Magnetite Composite Electrospun Scaffolds for Biomedical Applications; Polymers; Vol. 14, iss. 3

Xehetasun bibliografikoak
Parent link:	Polymers Vol. 14, iss. 3.— 2022.— [529, 17 p. ]
Egile korporatiboa:	Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий Научно-исследовательский центр "Физическое материаловедение и композитные материалы", Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Beste egile batzuk:	Pryadko A. Artyom, Botvin V. V. Vladimir Viktorovich, Mukhortova Yu. R. Yulia Ruslanovna, Pary (Pariy) I. O. Igor Olegovich, Vagner D. V. Dmitry Viktorovich, Laktionov P. P. Pavel Petrovich, Chernonosova V. S. Vera Sergeevna, Chelobanov B. P. Boris Pavlovich, Chernozem R. V. Roman Viktorovich, Surmeneva M. A. Maria Alexandrovna, Kholkin A. L. Andrei Leonidovich, Surmenev R. A. Roman Anatolievich
Gaia:	Novel hybrid magnetoactive composite scaffolds based on poly(3-hydroxybutyrate) (PHB), gelatin, and magnetite (Fe3O4) were fabricated by electrospinning. The morphology, structure, phase composition, and magnetic properties of composite scaffolds were studied. Fabrication procedures of PHB/gelatin and PHB/gelatin/Fe3O4 scaffolds resulted in the formation of both core-shell and ribbon-shaped structure of the fibers. In case of hybrid PHB/gelatin/Fe3O4 scaffolds submicron-sized Fe3O4 particles were observed in the surface layers of the fibers. The X-ray photoelectron spectroscopy results allowed the presence of gelatin on the fiber surface (N/C ratio–0.11) to be revealed. Incubation of the composite scaffolds in saline for 3 h decreased the amount of gelatin on the surface by more than ~75%. The differential scanning calorimetry results obtained for pure PHB scaffolds revealed a characteristic melting peak at 177.5 °C. The presence of gelatin in PHB/gelatin and PHB/gelatin/Fe3O4 scaffolds resulted in the decrease in melting temperature to 168–169 °C in comparison with pure PHB scaffolds due to the core-shell structure of the fibers. Hybrid scaffolds also demonstrated a decrease in crystallinity from 52.3% (PHB) to 16.9% (PHB/gelatin) and 9.2% (PHB/gelatin/Fe3O4). All the prepared scaffolds were non-toxic and saturation magnetization of the composite scaffolds with magnetite was 3.27 ± 0.22 emu/g, which makes them prospective candidates for usage in biomedical applications.
Hizkuntza:	ingelesa
Argitaratua:	2022
Gaiak:	труды учёных ТПУ электронный ресурс magnetoactive scaffold poly-3-hydroxybutyrate magnetite composite core-shell structure магнетит структура
Sarrera elektronikoa:	https://doi.org/10.3390/polym14030529
Formatua:	Baliabide elektronikoa Liburu kapitulua
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668014