Metal-Organic Frameworks (MOFs) for Cancer Therapy

Metal-Organic Frameworks (MOFs) for Cancer Therapy

Bibliographic Details
Parent link:Materials
Vol. 14, iss. 23.— 2021.— [7277, 10 p.]
Corporate Author: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Other Authors: Mohammad Reza Saeb, Navid Rabiee, Masoud Mozafari, Verpoort F. V. K. Frensis Valter Kornelius, Voskressensky L. G. Leonid, Rafael Luque
Summary:Title screen
MOFs exhibit inherent extraordinary features for diverse applications ranging from catalysis, storage, and optics to chemosensory and biomedical science and technology. Several procedures including solvothermal, hydrothermal, mechanochemical, electrochemical, and ultrasound techniques have been used to synthesize MOFs with tailored features. A continued attempt has also been directed towards functionalizing MOFs via “post-synthetic modification” mainly by changing linkers (by altering the type, length, functionality, and charge of the linkers) or node components within the MOF framework. Additionally, efforts are aimed towards manipulating the size and morphology of crystallite domains in the MOFs, which are aimed at enlarging their applications window. Today's knowledge of artificial intelligence and machine learning has opened new pathways to elaborate multiple nanoporous complex MOFs and nano-MOFs (NMOFs) for advanced theranostic, clinical, imaging, and diagnostic purposes. Successful accumulation of a photosensitizer in cancerous cells was a significant step in cancer therapy. The application of MOFs as advanced materials and systems for cancer therapy is the main scope beyond this perspective. Some challenging aspects and promising features in MOF-based cancer diagnosis and cancer therapy have also been discussed.
Published: 2021
Subjects:
электронный ресурс
труды учёных ТПУ
metal-organic frameworks (MOFs)
cancer therapy
biotechnology
nanomedicine
металлоорганические каркасы
терапия
рак
биотехнологии
наномедицина
Online Access:https://doi.org/10.3390/ma14237277
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=667940

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