Magnetoactive electrospun hybrid scaffolds based on poly(vinylidene fluoride-co-trifluoroethylene) and magnetite particles with varied sizes; Polymer Engineering and Science; Vol. 62, iss. 5
| Parent link: | Polymer Engineering and Science Vol. 62, iss. 5.— 2022.— [P. 1593-1607] |
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| সংস্থা লেখক: | |
| অন্যান্য লেখক: | , , , , , , , , , , |
| সংক্ষিপ্ত: | Title screen The development of functional magnetoactive materials fabricated in the form of electrospun scaffolds is of paramount importance for modern medicine and pharmaceuticals. To precisely control the morphology and magnetic properties of the composite magnetoactive scaffolds, the electrospinning conditions, incorporation method of magnetic particles into the polymer solution to avoid agglomeration, and the shape/size of the particles should be thoroughly studied. In this study, hybrid magnetoactive scaffolds based on poly(vinylidene fluoride-co-trifluoroethylene) (P(VDF-TrFE)), doped with either unmodified magnetite (Fe3O4) or magnetite particles modified with oleic acid (Fe3O4/OA), have been fabricated by electrospinning. Modification of magnetite particles by oleic acid results in the formation of nanosized particles in comparison with submicron-sized Fe3O4 particles (37 vs. 329 nm), which reveal a greater affinity to P(VDF-TrFE) due to their hydrophobic surface. Composite scaffolds prepared using 30 wt% polymer solution with 8 wt% Fe3O4 and Fe3O4/OA reveal saturation magnetization values of 9.14 and 5.8 emu/g, respectively. The saturation magnetization of composite scaffolds agrees well with the saturation magnetization of the initial magnetites. Considering the better dispersion of Fe3O4/OA in the polymer solution, a series of composite scaffolds with 4 and 12 wt% concentrations of magnetite have been studied. Cytotoxicity tests demonstrated that all the fabricated composite scaffolds are nontoxic to human cells. Variation of magnetite particles content in the polymer fibers enables to obtain composite scaffolds with tailored saturation magnetization, which can be potentially used as perspective magnetoactive and magnetoelectric materials for biomedical application. Режим доступа: по договору с организацией-держателем ресурса |
| ভাষা: | ইংরেজি |
| প্রকাশিত: |
2022
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://doi.org/10.1002/pen.25947 |
| বিন্যাস: | বৈদ্যুতিক গ্রন্থের অধ্যায় |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=667886 |
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| 200 | 1 | |a Magnetoactive electrospun hybrid scaffolds based on poly(vinylidene fluoride-co-trifluoroethylene) and magnetite particles with varied sizes |f V. V. Botvin, M. A. Surmeneva, Yu. R. Mukhortova [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: 52 tit.] | ||
| 330 | |a The development of functional magnetoactive materials fabricated in the form of electrospun scaffolds is of paramount importance for modern medicine and pharmaceuticals. To precisely control the morphology and magnetic properties of the composite magnetoactive scaffolds, the electrospinning conditions, incorporation method of magnetic particles into the polymer solution to avoid agglomeration, and the shape/size of the particles should be thoroughly studied. In this study, hybrid magnetoactive scaffolds based on poly(vinylidene fluoride-co-trifluoroethylene) (P(VDF-TrFE)), doped with either unmodified magnetite (Fe3O4) or magnetite particles modified with oleic acid (Fe3O4/OA), have been fabricated by electrospinning. Modification of magnetite particles by oleic acid results in the formation of nanosized particles in comparison with submicron-sized Fe3O4 particles (37 vs. 329 nm), which reveal a greater affinity to P(VDF-TrFE) due to their hydrophobic surface. Composite scaffolds prepared using 30 wt% polymer solution with 8 wt% Fe3O4 and Fe3O4/OA reveal saturation magnetization values of 9.14 and 5.8 emu/g, respectively. The saturation magnetization of composite scaffolds agrees well with the saturation magnetization of the initial magnetites. Considering the better dispersion of Fe3O4/OA in the polymer solution, a series of composite scaffolds with 4 and 12 wt% concentrations of magnetite have been studied. Cytotoxicity tests demonstrated that all the fabricated composite scaffolds are nontoxic to human cells. Variation of magnetite particles content in the polymer fibers enables to obtain composite scaffolds with tailored saturation magnetization, which can be potentially used as perspective magnetoactive and magnetoelectric materials for biomedical application. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | |t Polymer Engineering and Science | ||
| 463 | |t Vol. 62, iss. 5 |v [P. 1593-1607] |d 2022 | ||
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a магнитоактивная плазма | |
| 610 | 1 | |a медицина | |
| 610 | 1 | |a композиты | |
| 610 | 1 | |a магнетит | |
| 701 | 1 | |a Botvin |b V. V. |c chemist |c Senior Researcher of Tomsk Polytechnic University, Candidate of chemical sciences |f 1991- |g Vladimir Viktorovich |3 (RuTPU)RU\TPU\pers\47211 | |
| 701 | 1 | |a Surmeneva |b M. A. |c specialist in the field of material science |c engineer-researcher of Tomsk Polytechnic University, Associate Scientist |f 1984- |g Maria Alexandrovna |3 (RuTPU)RU\TPU\pers\31894 |9 15966 | |
| 701 | 1 | |a Mukhortova |b Yu. R. |c Chemical engineer |c Engineer of Tomsk Polytechnic University |f 1976- |g Yulia Ruslanovna |3 (RuTPU)RU\TPU\pers\46606 |9 22264 | |
| 701 | 1 | |a Belyakova |b Е. О. |c chemical engineer |c Research Engineer of Tomsk Polytechnic University |f 1997- |g Elizaveta Olegovna |3 (RuTPU)RU\TPU\pers\47215 | |
| 701 | 1 | |a Vagner |b D. V. |g Dmitry Viktorovich | |
| 701 | 1 | |a Chelobanov |b B. P. |g Boris Pavlovich | |
| 701 | 1 | |a Laktionov |b P. P. |g Pavel Petrovich | |
| 701 | 1 | |a Sukhinina |b E. V. |c specialist in the field of medical technology |c Research Engineer of Tomsk Polytechnic University |f 1997- |g Ekaterina Vladimirovna |3 (RuTPU)RU\TPU\pers\47213 |9 22793 | |
| 701 | 1 | |a Pershina |b A. G. |c biologist |c Associate Professor of Tomsk Polytechnic University, Candidate of biological sciences |f 1981- |g Aleksandra Gennadievna |3 (RuTPU)RU\TPU\pers\32466 |9 16414 | |
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| 701 | 1 | |a Surmenev |b R. A. |c physicist |c Associate Professor of Tomsk Polytechnic University, Senior researcher, Candidate of physical and mathematical sciences |f 1982- |g Roman Anatolievich |3 (RuTPU)RU\TPU\pers\31885 |9 15957 | |
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