Antibacterial Ferroelectric Hybrid Membranes Fabricated via Electrospinning for Wound Healing

Antibacterial Ferroelectric Hybrid Membranes Fabricated via Electrospinning for Wound Healing

Bibliografiske detaljer
Parent link:Membranes
Vol. 11, iss. 12.— 2021.— [986, 14 p.]
Corporate Authors: Национальный исследовательский Томский политехнический университет Инженерная школа новых производственных технологий Научно-образовательный центр Н. М. Кижнера, Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Научно-образовательный центр Б. П. Вейнберга
Andre forfattere: Lukiev I. V. Ivan Vasiljevich, Antipina L. S. Ludmila Sergeevna, Goreninsky (Goreninskii) S. I. Semen Igorevich, Tverdokhlebova T. S. Tamara Sergeevna, Vasilchenko D. V. Dmitry Vladimirovich, Nemoykina A. L. Anna Leonidovna, Goncharova D. A. Darjya Aleksandrovna, Svetlichniy V. A. Valery Anatoljevich, Dambaev G. T. Georgy Tsyrenovich, Buznik V. M. Vyacheslav Mikhaylovich, Bolbasov E. N. Evgeny Nikolaevich
Summary:Title screen
In the present study, wound healing ferroelectric membranes doped with zinc oxide nanoparticles were fabricated from vinylidene fluoride-tetrafluoroethylene copolymer and polyvinylpyrrolidone using the electrospinning technique. Five different ratios of vinylidene fluoride-tetrafluoroethylene to polyvinylpyrrolidone were used to control the properties of the membranes at a constant zinc oxide nanoparticle content. It was found that an increase of polyvinylpyrrolidone content leads to a decrease of the spinning solution conductivity and viscosity, causing a decrease of the average fiber diameter and reducing their strength and elongation. By means of X-ray diffraction and infrared spectroscopy, it was revealed that increased polyvinylpyrrolidone content leads to difficulty in crystallization of the vinylidene fluoride-tetrafluoroethylene copolymer in the ferroelectric Я-phase in membranes. Changing the ratio of vinylidene fluoride-tetrafluoroethylene copolymer and polyvinylpyrrolidone with a constant content of zinc oxide nanoparticles is an effective approach to control the antibacterial properties of membranes towards Staphylococcus aureus. After carrying out in vivo experiments, we found that ferroelectric hybrid membranes, containing from five to ten mass percent of PVP, have the greatest wound-healing effect for the healing of purulent wounds.
Sprog:engelsk
Udgivet: 2021
Fag:
электронный ресурс
труды учёных ТПУ
ferroelectrics
electrospinning
nanofibers
wound healing
сегнетоэлектрики
электропрядение
нановолокна
Online adgang:https://doi.org/10.3390/membranes11120986
Format: Electronisk Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=667106

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