Cell-Based Drug Delivery and Use of Nano-and Microcarriers for Cell Functionalization

Cell-Based Drug Delivery and Use of Nano-and Microcarriers for Cell Functionalization

Detalles Bibliográficos
Parent link:Advanced Healthcare Materials
Vol. 7, iss. 3.— 2018.— [P. 1–19]
Autor Corporativo: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Outros autores: Timin A. S. Aleksandr Sergeevich, Litvak M. M. Maksim Mikhaylovich, Gorin D. A. Dmitry Aleksandrovich, Atochina E. N. Elena Nikolaevna, Atochin D. N. Dmitry Nikolaevich, Sukhorukov G. B. Gleb Borisovich
Summary:Title screen
Cell functionalization with recently developed various nano- and microcarriers for therapeutics has significantly expanded the application of cell therapy and targeted drug delivery for the effective treatment of a number of diseases. The aim of this progress report is to review the most recent advances in cell-based drug vehicles designed as biological transporter platforms for the targeted delivery of different drugs. For the design of cell-based drug vehicles, different pathways of cell functionalization, such as covalent and noncovalent surface modifications, internalization of carriers are considered in greater detail together with approaches for cell visualization in vivo. In addition, several animal models for the study of cell-assisted drug delivery are discussed. Finally, possible future developments and applications of cell-assisted drug vehicles toward targeted transport of drugs to a designated location with no or minimal immune response and toxicity are addressed in light of new pathways in the field of nanomedicine.
Режим доступа: по договору с организацией-держателем ресурса
Publicado: 2018
Subjects:
электронный ресурс
труды учёных ТПУ
стволовые клетки
клеточная терапия
Acceso en liña:https://doi.org/10.1002/adhm.201700818
Formato: Electrónico Capítulo de libro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=666994

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